Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4kd7 9DR Dihydrofolate reductase 1.5.1.3

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4kd7 9DRDihydrofolate reductase 1.5.1.3 0.988
4kak 06UDihydrofolate reductase 1.5.1.3 0.772
3qlz QLZUncharacterized protein / 0.760
3qfx CP6Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.706
3k45 51PDihydrofolate reductase 1.5.1.3 0.698
2bl9 CP6Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.692
3jwc EKBDihydrofolate reductase / 0.686
3sgy 06WDihydrofolate reductase 1.5.1.3 0.685
3cse N22Uncharacterized protein / 0.672
2blb CP7Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.670
1u70 MTXDihydrofolate reductase 1.5.1.3 0.662
1hfp MOTDihydrofolate reductase 1.5.1.3 0.661
3d80 Q22Dihydrofolate reductase 1.5.1.3 0.660
2blc CP7Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.659
4ddr MMVDihydrofolate reductase 1.5.1.3 0.654
3qg2 CP6Bifunctional dihydrofolate reductase-thymidylate synthase / 0.653