Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4jpc 1M6 Beta-secretase 1 3.4.23.46

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4jpc 1M6Beta-secretase 1 3.4.23.46 0.916
4jp9 1M5Beta-secretase 1 3.4.23.46 0.870
4joo 1M4Beta-secretase 1 3.4.23.46 0.849
4jpe 1M7Beta-secretase 1 3.4.23.46 0.818
4djx 0KQBeta-secretase 1 3.4.23.46 0.778
4djv 0KMBeta-secretase 1 3.4.23.46 0.776
4djy 0KRBeta-secretase 1 3.4.23.46 0.776
4acu QN7Beta-secretase 1 3.4.23.46 0.764
4b0q GMFBeta-secretase 1 3.4.23.46 0.760
4djw 0KPBeta-secretase 1 3.4.23.46 0.757
4acx S8ZBeta-secretase 1 3.4.23.46 0.740
4b05 32DBeta-secretase 1 3.4.23.46 0.739
4b1c 1B1Beta-secretase 1 3.4.23.46 0.684
4b1e 6T6Beta-secretase 1 3.4.23.46 0.679
4b1d 6TGBeta-secretase 1 3.4.23.46 0.676
1c5n ESIProthrombin 3.4.21.5 0.669
4b70 WM9Beta-secretase 1 3.4.23.46 0.669
4azy 7F3Beta-secretase 1 3.4.23.46 0.660
1owk 303Urokinase-type plasminogen activator 3.4.21.73 0.656
2zfr 46UProthrombin 3.4.21.5 0.656
4b72 2FBBeta-secretase 1 3.4.23.46 0.656
2zhw 12UProthrombin 3.4.21.5 0.655
4az2 9MUProthrombin 3.4.21.5 0.652
1owd 497Urokinase-type plasminogen activator 3.4.21.73 0.651
2zi2 24UProthrombin 3.4.21.5 0.651
4b77 54MBeta-secretase 1 3.4.23.46 0.651
2zgx 29UProthrombin 3.4.21.5 0.650
4dju 0KKBeta-secretase 1 3.4.23.46 0.650