Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ivc 1J6 Tyrosine-protein kinase JAK1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4ivc 1J6Tyrosine-protein kinase JAK1 / 0.966
4ivb 1J5Tyrosine-protein kinase JAK1 / 0.940
4ivd 15TTyrosine-protein kinase JAK1 / 0.940
4iva 1J5Tyrosine-protein kinase JAK2 / 0.846
4ei4 0Q2Tyrosine-protein kinase JAK1 / 0.780
4e4l 0NHTyrosine-protein kinase JAK1 / 0.771
4ehz JAKTyrosine-protein kinase JAK1 / 0.764
4f09 JAKTyrosine-protein kinase JAK2 / 0.762
4i5c C5ITyrosine-protein kinase JAK1 / 0.745
4f08 1RSTyrosine-protein kinase JAK2 / 0.729
4e6d 0NUTyrosine-protein kinase JAK2 / 0.706
4e6q 0NVTyrosine-protein kinase JAK2 / 0.691
4ft7 H3KSerine/threonine-protein kinase Chk1 2.7.11.1 0.664
2erz HFScAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.662
4ewh T77Activated CDC42 kinase 1 / 0.657
4e4n 0NLTyrosine-protein kinase JAK1 / 0.655