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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ez5 0RS Cyclin-dependent kinase 6 2.7.11.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4ez5 0RSCyclin-dependent kinase 6 2.7.11.22 1.004
2vti LZ3Cyclin-dependent kinase 2 2.7.11.22 0.675
3ezv EZVCyclin-dependent kinase 2 2.7.11.22 0.670
3o0g 3O0Cyclin-dependent-like kinase 5 2.7.11.1 0.662
2w06 FRVCyclin-dependent kinase 2 2.7.11.22 0.659
3nun JMZ3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.658