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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ew2 DXY Trifunctional purine biosynthetic protein adenosine-3 2.1.2.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4ew2 DXYTrifunctional purine biosynthetic protein adenosine-3 2.1.2.2 1.139
4ew3 DXZTrifunctional purine biosynthetic protein adenosine-3 2.1.2.2 1.086
1rc1 KT3Trifunctional purine biosynthetic protein adenosine-3 2.1.2.2 0.857
1rbq KEUTrifunctional purine biosynthetic protein adenosine-3 2.1.2.2 0.849
1rbz KT5Trifunctional purine biosynthetic protein adenosine-3 2.1.2.2 0.809
1njs KEUTrifunctional purine biosynthetic protein adenosine-3 2.1.2.2 0.772
1rby KEUTrifunctional purine biosynthetic protein adenosine-3 2.1.2.2 0.703
1gar U89Phosphoribosylglycinamide formyltransferase / 0.669
1rbm KT5Trifunctional purine biosynthetic protein adenosine-3 2.1.2.2 0.669
1dhf FOLDihydrofolate reductase 1.5.1.3 0.650
4bqy FNTEgl nine homolog 1 / 0.650