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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4c4j X21 Dual specificity protein kinase TTK 2.7.12.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4c4j X21Dual specificity protein kinase TTK 2.7.12.1 1.145
4c4g 7RODual specificity protein kinase TTK 2.7.12.1 0.949
4c4h 7RODual specificity protein kinase TTK 2.7.12.1 0.924
4c4f 7CEDual specificity protein kinase TTK 2.7.12.1 0.728
4bdi HAUSerine/threonine-protein kinase Chk2 2.7.11.1 0.668
2p33 J07Mitogen-activated protein kinase 10 2.7.11.24 0.652
3b8r 887Vascular endothelial growth factor receptor 2 2.7.10.1 0.650
3w1f 1O5Dual specificity protein kinase TTK 2.7.12.1 0.650