sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ava | ACO | Acetyltransferase Pat | 2.3.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4ava | ACO | Acetyltransferase Pat | 2.3.1 | 1.367 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.818 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.811 | |
| 2q4v | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.790 | |
| 2vez | ACO | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.788 | |
| 1i12 | ACO | Glucosamine 6-phosphate N-acetyltransferase | / | 0.775 | |
| 2vxk | COA | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.761 | |
| 1bob | ACO | Histone acetyltransferase type B catalytic subunit | / | 0.756 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.754 | |
| 2vqy | ACO | AAC(6')-Ib | / | 0.751 | |
| 1ib1 | COT | Serotonin N-acetyltransferase | / | 0.749 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.738 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.737 | |
| 4cs0 | ACO | PanD regulatory factor | / | 0.736 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.731 | |
| 2prb | COA | Aminoglycoside 6-N-acetyltransferase type Ib11 | / | 0.729 | |
| 1v0c | ACO | AAC(6')-Ib | / | 0.726 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.725 | |
| 3gya | COA | GCN5-related N-acetyltransferase | / | 0.723 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.723 | |
| 4qvt | ACO | Acetyltransferase YpeA | 2.3.1 | 0.722 | |
| 2qir | COA | Aminoglycoside 6-N-acetyltransferase type Ib11 | / | 0.721 | |
| 1tiq | COA | Spermidine/spermine N(1)-acetyltransferase | / | 0.720 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.718 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.715 | |
| 2bsw | CAO | Probable acetyltransferase | / | 0.710 | |
| 4crz | ACO | PanD regulatory factor | / | 0.709 | |
| 3gy9 | COA | GCN5-related N-acetyltransferase | / | 0.707 | |
| 2bue | COA | AAC(6')-Ib | / | 0.706 | |
| 2ge3 | ACO | Probable acetyltransferase | / | 0.704 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.695 | |
| 4cry | ACO | PanD regulatory factor | / | 0.694 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.691 | |
| 1cjw | COT | Serotonin N-acetyltransferase | / | 0.689 | |
| 2zpa | ACO | tRNA(Met) cytidine acetyltransferase TmcA | / | 0.688 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.687 | |
| 1l0c | COT | Serotonin N-acetyltransferase | / | 0.685 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.685 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.683 | |
| 3s6f | COA | Uncharacterized protein | / | 0.681 | |
| 4r87 | COA | Spermidine N(1)-acetyltransferase | / | 0.680 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.679 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.676 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.676 | |
| 1z4r | ACO | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.675 | |
| 2vbq | BSJ | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.675 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.674 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.668 | |
| 4jxr | ACO | Acetyltransferase | / | 0.668 | |
| 5kf1 | COA | Predicted acetyltransferase | / | 0.666 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.665 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.665 | |
| 3sxn | COA | N-acetyltransferase Eis | / | 0.662 | |
| 4kub | COA | Uncharacterized protein | / | 0.661 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.659 | |
| 4ucn | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.658 | |
| 2wpw | ACO | Orf14 | / | 0.654 | |
| 3zj0 | ACO | Putative acetyltransferase OgpAT | / | 0.654 | |
| 2jdc | CAO | Probable acetyltransferase | / | 0.653 | |
| 2ozg | COA | GCN5-related N-acetyltransferase | / | 0.653 | |
| 1kuv | CA5 | Serotonin N-acetyltransferase | / | 0.652 | |
| 1qsr | ACO | HAT A1 | / | 0.652 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.651 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.650 | |
| 4r3k | COA | N-alpha-acetyltransferase | 2.3.1 | 0.650 |