Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3zrr PXG Serine-pyruvate aminotransferase (AgxT)

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3zrr PXGSerine-pyruvate aminotransferase (AgxT) / 1.228
3tfu PL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 2.6.1.62 0.721
4ao4 PLKBeta-transaminase / 0.694
2pb2 PLPAcetylornithine/succinyldiaminopimelate aminotransferase 2.6.1.11 0.690
4jf1 PLPAcetylornithine/succinyldiaminopimelate aminotransferase 2.6.1.11 0.686
4d96 5PAD-cysteine desulfhydrase / 0.679
4wlj IK2Kynurenine--oxoglutarate transaminase 1 2.6.1.7 0.678
4gdy 0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2.6.1.39 0.672
4ge7 0K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2.6.1.39 0.672
4geb 0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2.6.1.39 0.671
2fq6 P3FCystathionine beta-lyase MetC 4.4.1.8 0.669
4ge4 0KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2.6.1.39 0.666
3vax PLPUncharacterized protein / 0.664
4ge9 0L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2.6.1.39 0.664
4w5k PLPAspartate aminotransferase, mitochondrial / 0.664
2gqn BLPCystathionine beta-lyase MetC 4.4.1.8 0.661
3tqx PLP2-amino-3-ketobutyrate coenzyme A ligase / 0.661
4zm3 PLPAminotransferase / 0.661
1b9i PXG3-amino-5-hydroxybenzoate synthase 4.2.1.144 0.658
2hp2 KE4Glutamate-1-semialdehyde 2,1-aminomutase 5.4.3.8 0.657
4eb7 PLPCysteine desulfurase IscS 2 / 0.657
2ykv IK2Beta-transaminase / 0.655
4ba5 PXGProbable aminotransferase / 0.651