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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3tza TZG Glutamate receptor 2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3tza TZGGlutamate receptor 2 / 1.104
4dld TZGGlutamate receptor ionotropic, kainate 1 / 0.884
2qs1 UB1Glutamate receptor ionotropic, kainate 1 / 0.787
3rt8 CWDGlutamate receptor 3 / 0.781
2wky IBCGlutamate receptor ionotropic, kainate 1 / 0.749
3kfm KAIGlutamate receptor 4 / 0.723
3c36 KAIGlutamate receptor ionotropic, kainate 1 / 0.710
3h03 UBPGlutamate receptor 2 / 0.709
4f31 KAIGlutamate receptor 3 / 0.705
2ojt UBAGlutamate receptor ionotropic, kainate 1 / 0.693
3c34 KAIGlutamate receptor ionotropic, kainate 1 / 0.691
1fw0 KAIGlutamate receptor 2 / 0.681
3s2v 3HUGlutamate receptor ionotropic, kainate 1 / 0.680
1gsu GTXGlutathione S-transferase 2 2.5.1.18 0.677
1vso AT1Glutamate receptor ionotropic, kainate 1 / 0.674
3t7s SAMUncharacterized protein / 0.674
2c4j GSOGlutathione S-transferase Mu 2 2.5.1.18 0.667
1ftl DNQGlutamate receptor 2 / 0.657
4f3g KAIGlutamate receptor 3 / 0.657
1hfq MOTDihydrofolate reductase 1.5.1.3 0.652
2hv9 SFGmRNA cap guanine-N7 methyltransferase 2.1.1.56 0.652
3c35 KAIGlutamate receptor ionotropic, kainate 1 / 0.652
1opm IYGPeptidyl-glycine alpha-amidating monooxygenase 1.14.17.3 0.651