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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3qru X19 Cyclin-dependent kinase 2 2.7.11.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3qru X19Cyclin-dependent kinase 2 2.7.11.22 1.011
3r8l Z30Cyclin-dependent kinase 2 2.7.11.22 0.838
3r8p Z46Cyclin-dependent kinase 2 2.7.11.22 0.754
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
1vyw 292Cyclin-dependent kinase 2 2.7.11.22 0.672
1gii 1PUCyclin-dependent kinase 2 2.7.11.22 0.662
1coy ANDCholesterol oxidase 1.1.3.6 0.660
4e5f 0N7Polymerase acidic protein / 0.660
2c3k ABOSerine/threonine-protein kinase Chk1 2.7.11.1 0.657
2r3r 6SCCyclin-dependent kinase 2 2.7.11.22 0.654
2vto LZ8Cyclin-dependent kinase 2 2.7.11.22 0.650