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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3lcd BDY Macrophage colony-stimulating factor 1 receptor 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
3lcd BDYMacrophage colony-stimulating factor 1 receptor 2.7.10.1 0.853
4e5i 0N9Polymerase acidic protein / 0.744
4yzc STUSerine/threonine-protein kinase/endoribonuclease IRE1 2.7.11.1 0.683
4ans VGHALK tyrosine kinase receptor 2.7.10.1 0.674
5dr6 SKEAurora kinase A 2.7.11.1 0.668
2cgw 3C3Serine/threonine-protein kinase Chk1 2.7.11.1 0.663
2z7q ACPRibosomal protein S6 kinase alpha-1 2.7.11.1 0.663
4e5f 0N7Polymerase acidic protein / 0.660