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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3l5d BDV Beta-secretase 1 3.4.23.46

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3l5d BDVBeta-secretase 1 3.4.23.46 0.983
3l5e BDWBeta-secretase 1 3.4.23.46 0.843
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4b0q GMFBeta-secretase 1 3.4.23.46 0.689
4djy 0KRBeta-secretase 1 3.4.23.46 0.685
4acu QN7Beta-secretase 1 3.4.23.46 0.679
1c5n ESIProthrombin 3.4.21.5 0.665
2oah QINBeta-secretase 1 3.4.23.46 0.665
4djx 0KQBeta-secretase 1 3.4.23.46 0.665
4e5f 0N7Polymerase acidic protein / 0.660
3l5b BDOBeta-secretase 1 3.4.23.46 0.657
4fub 4UPUrokinase-type plasminogen activator 3.4.21.73 0.651
4fud 6UPUrokinase-type plasminogen activator 3.4.21.73 0.650