Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3jwm 5WB Dihydrofolate reductase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3jwm 5WBDihydrofolate reductase / 1.016
3eek 53SUncharacterized protein / 0.747
3qly 55VUncharacterized protein / 0.734
3sai 9DRDihydrofolate reductase / 0.727
3sh2 5DRDihydrofolate reductase 1.5.1.3 0.716
3qlx QLRUncharacterized protein / 0.698
3dfr MTXDihydrofolate reductase 1.5.1.3 0.680
3jwc EKBDihydrofolate reductase / 0.678
3srs M23Dihydrofolate reductase 1.5.1.3 0.661
3d80 Q22Dihydrofolate reductase 1.5.1.3 0.656
4ixf IXFDihydrofolate reductase 1.5.1.3 0.654
1e26 GPBDihydrofolate reductase 1.5.1.3 0.653
3ia4 MTXDihydrofolate reductase / 0.650