Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3inm NDP Isocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3inm NDPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 1.161
2cmv NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 1.022
4kzo NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 1.017
2cmj NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 1.012
4l03 NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.987
1t0l NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.943
4l04 NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.936
4umx NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.867
4umy NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.860
4l06 NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.837
4aov NAPIsocitrate dehydrogenase [NADP] / 0.821
2qfv NAPIsocitrate dehydrogenase [NADP], mitochondrial 1.1.1.42 0.789
2qfx NDPIsocitrate dehydrogenase [NADP], mitochondrial 1.1.1.42 0.770
3flk NAITartrate dehydrogenase/decarboxylase 1.1.1.93 0.742
4f7i NAD3-isopropylmalate dehydrogenase 1.1.1.85 0.735
2d4v NADIsocitrate dehydrogenase [NADP] / 0.730
4xxv NAD3-isopropylmalate dehydrogenase / 0.729
4wuo NAD3-isopropylmalate dehydrogenase 1.1.1.85 0.724
2d1c NAPIsocitrate dehydrogenase [NADP] 1.1.1.42 0.723
1t09 NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.714
1xkd NAPIsocitrate dehydrogenase [NADP] / 0.688
2y42 NAD3-isopropylmalate dehydrogenase 1.1.1.85 0.660