Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3i8a N22 Dihydrofolate reductase 1.5.1.3

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3i8a N22Dihydrofolate reductase 1.5.1.3 1.146
3sh2 5DRDihydrofolate reductase 1.5.1.3 0.878
3sai 9DRDihydrofolate reductase / 0.832
4xe6 06UDihydrofolate reductase 1.5.1.3 0.725
3sa2 7DRDihydrofolate reductase / 0.685
3qlz QLZUncharacterized protein / 0.683
1hfr MOTDihydrofolate reductase 1.5.1.3 0.681
1dds MTXDihydrofolate reductase 1.5.1.3 0.673
4h95 06UDihydrofolate reductase 1.5.1.3 0.673
3sru Q26Dihydrofolate reductase 1.5.1.3 0.661
3d80 Q22Dihydrofolate reductase 1.5.1.3 0.659
3gph OIDCytochrome P450 2E1 1.14.13 0.659
4ddr MMVDihydrofolate reductase 1.5.1.3 0.657
4p68 MTXDihydrofolate reductase / 0.657
3qls 55VDihydrofolate reductase 1.5.1.3 0.650