Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3hb8 UMP Thymidylate synthase 2.1.1.45

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3hb8 UMPThymidylate synthase 2.1.1.45 0.985
4ein NOHThymidylate synthase 2.1.1.45 0.700
1bp6 UMPThymidylate synthase / 0.675
1f28 UMPThymidylate synthase 2.1.1.45 0.673
4psg NOHThymidylate synthase / 0.672
2g8a UMPThymidylate synthase / 0.671
2wba NDPTrypanothione reductase 1.8.1.12 0.668
4dq1 UMPThymidylate synthase / 0.668
4dpd UMPBifunctional dihydrofolate reductase-thymidylate synthase / 0.667
3lzw NAPFerredoxin--NADP reductase 2 1.18.1.2 0.661
4cnz ADPNitrogen regulatory protein P-II 1 / 0.660
5by6 UMPThymidylate synthase / 0.657
1tsy UMPThymidylate synthase / 0.655
1vc9 ATPDiadenosine hexaphosphate hydrolase 3.6.1.61 0.655
3dk4 NDPGlutathione reductase, mitochondrial 1.8.1.7 0.652