Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3bhr THG Thymidylate synthase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3bhr THGThymidylate synthase / 0.886
1tys DHFThymidylate synthase / 0.772
4gev CB3Thymidylate synthase / 0.721
3bhl THGThymidylate synthase / 0.719
4knz CB3Thymidylate synthase / 0.712
1trg CB3Thymidylate synthase / 0.710
2fto CB3Thymidylate synthase / 0.697
1jtu LYBThymidylate synthase / 0.692
2bbq PFGThymidylate synthase / 0.689
3bgx MEFThymidylate synthase / 0.681
1kce CB3Thymidylate synthase / 0.677
4eil CB3Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.653