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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2zgz GNP Plasmid segregation protein ParM

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2zgz GNPPlasmid segregation protein ParM / 1.085
4a61 ANPPlasmid segregation protein ParM / 0.917
2zgy GDPPlasmid segregation protein ParM / 0.900
1mwm ADPPlasmid segregation protein ParM / 0.775
1dej ATPMajor actin / 0.753
4a2b AGSCell division protein FtsA / 0.753
4eht ADP2-hydroxyisocaproyl-CoA dehydratase activator / 0.752
4ehu ANP2-hydroxyisocaproyl-CoA dehydratase activator / 0.750
3a5o ATPMajor actin / 0.741
4a62 ANPPlasmid segregation protein ParM / 0.733
2q36 ATPActin, alpha skeletal muscle / 0.726
3mn9 ATPActin-5C / 0.723
3mn6 ATPActin-5C / 0.720
3a5m ATPMajor actin / 0.717
1wua ATPActin, alpha skeletal muscle / 0.716
3daw ATPActin, alpha skeletal muscle / 0.714
4a2a ATPCell division protein FtsA / 0.714
2q97 ATPActin, alpha skeletal muscle / 0.708
5ce3 ATPActin / 0.707
1mdu ATPActin, alpha skeletal muscle / 0.706
1lot ATPActin, alpha skeletal muscle / 0.704
2fsn ADPArchaeal actin homolog / 0.702
1kxp ATPActin, alpha skeletal muscle / 0.701
1nmd ATPMajor actin / 0.700
1qz5 ATPActin, alpha skeletal muscle / 0.698
1yxq ATPActin, alpha skeletal muscle / 0.698
3chw ATPMajor actin / 0.698
4pkg ATPActin, alpha skeletal muscle / 0.698
1t44 ATPActin, alpha skeletal muscle / 0.697
3d2e ATPHeat shock protein homolog SSE1 / 0.694
4pl8 ATPActin, alpha skeletal muscle / 0.694
1nm1 ATPMajor actin / 0.692
2v51 ATPActin, alpha skeletal muscle / 0.688
4pkh ADPActin, alpha skeletal muscle / 0.687
2a41 ATPActin, alpha skeletal muscle / 0.685
1s22 ATPActin, alpha skeletal muscle / 0.684
3eks ATPActin-5C / 0.681
3mn7 ATPActin-5C / 0.675
2p9k ATPActin-related protein 2 / 0.674
3wt0 ATPCell division protein FtsA / 0.668
1e4g ATPCell division protein FtsA / 0.665
1eqy ATPActin, alpha skeletal muscle / 0.664
1h1v ATPActin, alpha skeletal muscle / 0.664
4jhd ANPActin-5C / 0.664
3m6g ATPActin, alpha skeletal muscle / 0.663
4rwt ANPActin-5C / 0.663
4k41 ATPActin, alpha skeletal muscle / 0.658
4b9q ATPChaperone protein DnaK / 0.654
2oan ATPActin, cytoplasmic 1 / 0.652
1nlv ATPMajor actin / 0.651