Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2yy2 IBM High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2yy2 IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.889
3qi4 IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.699
1rkp IBMcGMP-specific 3',5'-cyclic phosphodiesterase / 0.667
1soj IBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B 3.1.4.17 0.655
3itu IBMcGMP-dependent 3',5'-cyclic phosphodiesterase 3.1.4.17 0.652