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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2wqo VGK Serine/threonine-protein kinase Nek2 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2wqo VGKSerine/threonine-protein kinase Nek2 2.7.11.1 1.018
2xkd T3MSerine/threonine-protein kinase Nek2 2.7.11.1 0.838
2xke WI2Serine/threonine-protein kinase Nek2 2.7.11.1 0.833
2xkf BX1Serine/threonine-protein kinase Nek2 2.7.11.1 0.795
2xk3 XK3Serine/threonine-protein kinase Nek2 2.7.11.1 0.764
2xk8 5R1Serine/threonine-protein kinase Nek2 2.7.11.1 0.750
2xkc 4VQSerine/threonine-protein kinase Nek2 2.7.11.1 0.739
3bqr 4RBDeath-associated protein kinase 3 / 0.699
4afe GGYSerine/threonine-protein kinase Nek2 2.7.11.1 0.699
2xk4 OL2Serine/threonine-protein kinase Nek2 2.7.11.1 0.695
3axw TIDCasein kinase II subunit alpha 2.7.11.1 0.690
2xk6 EQHSerine/threonine-protein kinase Nek2 2.7.11.1 0.681
4a4x JUPSerine/threonine-protein kinase Nek2 2.7.11.1 0.680
3pe1 3NGCasein kinase II subunit alpha 2.7.11.1 0.671
3nga 3NGCasein kinase II subunit alpha 2.7.11.1 0.669
3pe2 E1BCasein kinase II subunit alpha 2.7.11.1 0.666
4qny ANPMitogen activated protein kinase, putative / 0.652