Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2pvy ACP Fibroblast growth factor receptor 2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2pvy ACPFibroblast growth factor receptor 2 / 0.767
3b2t M33Fibroblast growth factor receptor 2 / 0.700
4xhg ADPUncharacterized protein / 0.697
3uim ANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 2.7.10.1 0.695
1e1v CMGCyclin-dependent kinase 2 2.7.11.22 0.688
4ckj ADNProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.678
4cki ADNProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.676
4j98 ACPFibroblast growth factor receptor 2 / 0.675
2pvr ANPCasein kinase II subunit alpha 2.7.11.1 0.672
2qo9 ANPEphrin type-A receptor 3 2.7.10.1 0.671
4gvj ADPNon-receptor tyrosine-protein kinase TYK2 2.7.10.2 0.669
4j97 ACPFibroblast growth factor receptor 2 / 0.667
2pzp ACPFibroblast growth factor receptor 2 / 0.666
2py3 ACPFibroblast growth factor receptor 2 / 0.665
4dca ADPAminoglycoside phosphotransferase / 0.663
3blq ATPCyclin-dependent kinase 9 2.7.11.22 0.660
2w5b AGSSerine/threonine-protein kinase Nek2 2.7.11.1 0.659
5eg3 ACPFibroblast growth factor receptor 2 / 0.659
5cu6 ATPCasein kinase II subunit alpha 2.7.11.1 0.658
4gt3 ATPMitogen-activated protein kinase 1 2.7.11.24 0.657
2qoq ANPEphrin type-A receptor 3 2.7.10.1 0.655
4s34 ANPMitogen-activated protein kinase 1 2.7.11.24 0.654
4w9w YDJBMP-2-inducible protein kinase 2.7.11.1 0.654
1h1q 2A6Cyclin-dependent kinase 2 2.7.11.22 0.650