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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2ojf 4PY cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2ojf 4PYcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.927
2jds L20cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.846
2uzu L20cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.803
2f7x 4EAcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.771
2uzw SS4cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.769
3kkv B99cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.738
2oh0 2PYcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.734
2uzv SS5cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.719
5dgz L20Serine/threonine-protein kinase pim-1 2.7.11.1 0.712
3l9n L9NcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.666
1rej B1LcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.656
2f7z 6EAcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.656
3i4b Z48Glycogen synthase kinase-3 beta 2.7.11.26 0.654