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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2izh BTN Streptavidin

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2izh BTNStreptavidin / 1.034
2izf BTNStreptavidin / 1.028
2y3f BTNStreptavidin / 1.028
3ry2 BTNStreptavidin / 1.025
3wyq BTNStreptavidin / 1.025
1nqm BTNStreptavidin / 1.020
1mk5 BTNStreptavidin / 1.015
2rtg BTNStreptavidin / 1.007
2rtd BTNStreptavidin / 1.006
2rtf BTNStreptavidin / 1.006
2izi BTNStreptavidin / 0.996
2rte BTNStreptavidin / 0.994
4gda BTNStreptavidin / 0.993
3wyp BSOStreptavidin / 0.991
1luq BTNStreptavidin / 0.982
2izj BTNStreptavidin / 0.979
4dne DTBStreptavidin / 0.977
3wzn BTNStreptavidin / 0.970
2zsc BTNTamavidin2 / 0.969
1i9h BNIStreptavidin / 0.967
1n43 BTNStreptavidin / 0.964
1n9m BTNStreptavidin / 0.957
3rdo BTNStreptavidin / 0.952
4gd9 BTNStreptavidin / 0.952
1df8 BTNStreptavidin / 0.949
1swe BTNStreptavidin / 0.941
3rdq DTBStreptavidin / 0.941
1mep BTNStreptavidin / 0.925
1lcw SHMStreptavidin / 0.920
4yvb BTNStreptavidin / 0.918
1stp BTNStreptavidin / 0.916
4z28 BTNHoefavidin / 0.916
2izl IMIStreptavidin / 0.913
1ndj BTNStreptavidin / 0.910
1swg BTNStreptavidin / 0.907
4bx7 B4FStreptavidin / 0.904
2uyw BTNAvd protein / 0.901
1swr BTNStreptavidin / 0.900
1nc9 IMIStreptavidin / 0.898
3ew2 BTNHypothetical conserved protein / 0.895
2fhl BNIAvidin-related protein 4/5 / 0.894
2rtp IMIStreptavidin / 0.894
1rxj BNIStreptavidin / 0.887
1y52 BTNAvidin-related protein 4/5 / 0.879
2fhn BNIAvidin-related protein 4/5 / 0.878
1swt BTNStreptavidin / 0.873
4bcs BTNAvidin-related protein 4/5 / 0.870
1swn BTNStreptavidin / 0.862
2rto IMIStreptavidin / 0.852
1swp BTNStreptavidin / 0.841
2rtq IMIStreptavidin / 0.840
3t2w BTNAvidin/streptavidin / 0.840
1lcz BH7Streptavidin / 0.837
2rtn IMIStreptavidin / 0.833
4bj8 BTNAvidin / 0.830
3vgw NVZAvidin / 0.827
3vhi VHIAvidin / 0.811
1swp BTQStreptavidin / 0.806
2rtm IMIStreptavidin / 0.800
2rtl IMIStreptavidin / 0.775
2jgs BTNAvidin / 0.768
1ij8 BNIAvidin / 0.751
2izg BTNStreptavidin / 0.748
1swd BTNStreptavidin / 0.732
2avi BTNAvidin / 0.730
4ggz BTNBll1558 protein / 0.701
1rxh BNIStreptavidin / 0.697
3vhm NPKAvidin / 0.685
1avd BTNAvidin / 0.684
1ldq SHMAvidin / 0.679
2rtk GLLStreptavidin / 0.656
2nmt NHMGlycylpeptide N-tetradecanoyltransferase 2.3.1.97 0.652