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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2izf BTN Streptavidin

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2izf BTNStreptavidin / 1.050
2y3f BTNStreptavidin / 1.046
3ry2 BTNStreptavidin / 1.043
3wyq BTNStreptavidin / 1.040
1mk5 BTNStreptavidin / 1.034
2izi BTNStreptavidin / 1.032
2izh BTNStreptavidin / 1.028
2rtg BTNStreptavidin / 1.026
2izg BTNStreptavidin / 1.025
2rtd BTNStreptavidin / 1.024
1nqm BTNStreptavidin / 1.019
2rtf BTNStreptavidin / 1.019
2rte BTNStreptavidin / 1.012
4gda BTNStreptavidin / 1.006
1i9h BNIStreptavidin / 1.000
2izj BTNStreptavidin / 0.992
1swe BTNStreptavidin / 0.991
3wyp BSOStreptavidin / 0.990
1n43 BTNStreptavidin / 0.982
1luq BTNStreptavidin / 0.981
2zsc BTNTamavidin2 / 0.977
1n9m BTNStreptavidin / 0.975
4dne DTBStreptavidin / 0.975
3rdo BTNStreptavidin / 0.970
4gd9 BTNStreptavidin / 0.970
3wzn BTNStreptavidin / 0.969
1df8 BTNStreptavidin / 0.963
3rdq DTBStreptavidin / 0.943
4bx7 B4FStreptavidin / 0.941
4yvb BTNStreptavidin / 0.938
2izl IMIStreptavidin / 0.932
1swr BTNStreptavidin / 0.931
1stp BTNStreptavidin / 0.929
1ndj BTNStreptavidin / 0.925
1lcw SHMStreptavidin / 0.924
1mep BTNStreptavidin / 0.923
1swt BTNStreptavidin / 0.907
2uyw BTNAvd protein / 0.907
3ew2 BTNHypothetical conserved protein / 0.901
1swg BTNStreptavidin / 0.892
1rxj BNIStreptavidin / 0.886
1nc9 IMIStreptavidin / 0.882
2fhl BNIAvidin-related protein 4/5 / 0.880
2fhn BNIAvidin-related protein 4/5 / 0.878
1y52 BTNAvidin-related protein 4/5 / 0.874
1lcz BH7Streptavidin / 0.870
4bcs BTNAvidin-related protein 4/5 / 0.869
4z28 BTNHoefavidin / 0.869
2rtp IMIStreptavidin / 0.857
1swp BTNStreptavidin / 0.855
2rto IMIStreptavidin / 0.834
2c4i BTNAvidin / 0.833
4bj8 BTNAvidin / 0.808
3vgw NVZAvidin / 0.807
3vhi VHIAvidin / 0.796
2rtm IMIStreptavidin / 0.794
2rtn IMIStreptavidin / 0.790
1swd BTNStreptavidin / 0.786
2jgs BTNAvidin / 0.785
1swn BTNStreptavidin / 0.784
2rtl IMIStreptavidin / 0.770
2rtq IMIStreptavidin / 0.759
1ij8 BNIAvidin / 0.751
3vhh VHHAvidin / 0.716
3vhm NPKAvidin / 0.702
1ldq SHMAvidin / 0.693
1rxh BNIStreptavidin / 0.692
4ggz BTNBll1558 protein / 0.684
2avi BTNAvidin / 0.676
1avd BTNAvidin / 0.668
3t2w BTNAvidin/streptavidin / 0.659
2rtk GLLStreptavidin / 0.653
4b11 NHWGlycylpeptide N-tetradecanoyltransferase / 0.651