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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2gqn BLP Cystathionine beta-lyase MetC 4.4.1.8

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2gqn BLPCystathionine beta-lyase MetC 4.4.1.8 1.052
2fq6 P3FCystathionine beta-lyase MetC 4.4.1.8 1.017
1cl2 PPGCystathionine beta-lyase MetC 4.4.1.8 0.944
4itx IN5Cystathionine beta-lyase MetC 4.4.1.8 0.857
2bwp PLG5-aminolevulinate synthase 2.3.1.37 0.726
1akb PPDAspartate aminotransferase, mitochondrial 2.6.1.1 0.716
1akc PPEAspartate aminotransferase, mitochondrial 2.6.1.1 0.702
4eb5 PLPCysteine desulfurase IscS 2 / 0.702
1oxo IK2Aspartate aminotransferase, mitochondrial 2.6.1.1 0.695
1map KETAspartate aminotransferase, mitochondrial 2.6.1.1 0.689
1x28 PGUAspartate aminotransferase 2.6.1.1 0.689
1ivr CBAAspartate aminotransferase, mitochondrial 2.6.1.1 0.681
4adc PLPSuccinylornithine transaminase 2.6.1.81 0.681
1arh PPDAspartate aminotransferase 2.6.1.1 0.674
4wxg 2BOSerine hydroxymethyltransferase / 0.664
3tqx PLP2-amino-3-ketobutyrate coenzyme A ligase / 0.662
3zrr PXGSerine-pyruvate aminotransferase (AgxT) / 0.661
1dfo PLGSerine hydroxymethyltransferase 2.1.2.1 0.659
4oma LCSMethionine gamma-lyase / 0.659
4obu PLPPyridoxal-dependent decarboxylase domain protein / 0.656
4emy PLPAminotransferase class I and II / 0.655
4w5k PLPAspartate aminotransferase, mitochondrial / 0.652