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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2fxv 5GP Xanthine phosphoribosyltransferase 2.4.2.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2fxv 5GPXanthine phosphoribosyltransferase 2.4.2.22 0.970
1qk3 5GPHypoxanthine-guanine-xanthine phosphoribosyltransferase 2.4.2.22 0.675
3gep 24HHypoxanthine-guanine phosphoribosyltransferase 2.4.2.8 0.674
2prz OMPOrotate phosphoribosyltransferase 1 2.4.2.10 0.662
3ggj 25HHypoxanthine-guanine phosphoribosyltransferase 2.4.2.8 0.654