Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2f7e 2EA cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2f7e 2EAcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 1.046
2oh0 2PYcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.821
3kkv B99cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.814
2jds L20cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.811
1ydr IQPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.762
2c1a I5ScAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.748
4e5i 0N9Polymerase acidic protein / 0.744
2uzw SS4cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.730
1ydt IQBcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.724
2gnl H52cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.719
2f2u M77Rho-associated protein kinase 2 2.7.11.1 0.718
2jdv L20cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.709
3l9n L9NcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.691
4agu D15Cyclin-dependent kinase-like 1 / 0.690
3vqh IQBcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.675
1p2a 5BNCyclin-dependent kinase 2 2.7.11.22 0.673
3hzt J60Calmodulin-like domain protein kinase isoform 3 / 0.673
2gni M77cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.670
3q9w EMOCasein kinase II subunit alpha 2.7.11.1 0.668
2jdt I5ScAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.663
4fsz HK8Serine/threonine-protein kinase Chk1 2.7.11.1 0.663
4e5f 0N7Polymerase acidic protein / 0.660
4jq8 KJ8Epidermal growth factor receptor 2.7.10.1 0.660
2c1b CQPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.658
2c3k ABOSerine/threonine-protein kinase Chk1 2.7.11.1 0.656
4ag8 AXIVascular endothelial growth factor receptor 2 2.7.10.1 0.652
2vag V25Dual specificity protein kinase CLK1 2.7.12.1 0.650
2vti LZ3Cyclin-dependent kinase 2 2.7.11.22 0.650