Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2d1c NAP Isocitrate dehydrogenase [NADP] 1.1.1.42

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2d1c NAPIsocitrate dehydrogenase [NADP] 1.1.1.42 1.365
1xkd NAPIsocitrate dehydrogenase [NADP] / 0.992
2cmj NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.848
4l06 NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.800
2cmv NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.796
2d4v NADIsocitrate dehydrogenase [NADP] / 0.789
4wuo NAD3-isopropylmalate dehydrogenase 1.1.1.85 0.787
1t0l NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.774
4l04 NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.762
4kzo NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.761
4f7i NAD3-isopropylmalate dehydrogenase 1.1.1.85 0.747
4umy NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.740
3inm NDPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.723
4aov NAPIsocitrate dehydrogenase [NADP] / 0.690
3flk NAITartrate dehydrogenase/decarboxylase 1.1.1.93 0.689
4umx NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.687
2qfx NDPIsocitrate dehydrogenase [NADP], mitochondrial 1.1.1.42 0.674
2y42 NAD3-isopropylmalate dehydrogenase 1.1.1.85 0.672
4xxv NAD3-isopropylmalate dehydrogenase / 0.671
4l03 NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.658
3wnz ADPAlanine--anticapsin ligase / 0.651
4ylh YE1(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase / 0.651
1kph SAHCyclopropane mycolic acid synthase 1 2.1.1.79 0.650