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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2cgw 3C3 Serine/threonine-protein kinase Chk1 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1bxd ANPOsmolarity sensor protein EnvZ 2.7.13.3 0.744
1c4y IH3Prothrombin 3.4.21.5 0.744
1crb RTLRetinol-binding protein 1 / 0.744
1cx2 S58Prostaglandin G/H synthase 2 1.14.99.1 0.744
1d3d BZTProthrombin 3.4.21.5 0.744
1diu BDMDihydrofolate reductase 1.5.1.3 0.744
1e3k R18Progesterone receptor / 0.744
1e7a PFLSerum albumin / 0.744
1eh4 IC1Casein kinase I homolog 1 2.7.11.1 0.744
1f0q EMOCasein kinase II subunit alpha 2.7.11.1 0.744
1fdu ESTEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.744
1g9c BABBotulinum neurotoxin type B 3.4.24.69 0.744
1h0w 207Cyclin-dependent kinase 2 2.7.11.22 0.744
1hk5 T44Serum albumin / 0.744
1hni AAAGag-Pol polyprotein 2.7.7.49 0.744
1hnv TBOGag-Pol polyprotein 2.7.7.49 0.744
1hqu HBYGag-Pol polyprotein 2.7.7.49 0.744
1i05 LTLMajor urinary protein 6 / 0.744
1i7g CPQPeroxisome proliferator-activated receptor alpha / 0.744
1ikv EFZGag-Pol polyprotein 2.7.7.49 0.744
1iky MSDGag-Pol polyprotein 2.7.7.49 0.744
1irj CPSProtein S100-A9 / 0.744
1jla TNKGag-Pol polyprotein 2.7.7.49 0.744
1jlg UC1Gag-Pol polyprotein 2.7.7.49 0.744
1jlq SBNGag-Pol polyprotein 2.7.7.49 0.744
1jut LYDThymidylate synthase / 0.744
1jx0 DFVChalcone--flavonone isomerase 1 5.5.1.6 0.744
1kb9 SMACytochrome b / 0.744
1kgj FL8Transthyretin / 0.744
1kqw RTLCellular retinol-binding protein type II / 0.744
1kzu RG1Light-harvesting protein B-800/850 alpha chain / 0.744
1kzu RG1Light-harvesting protein B-800/850 beta chain / 0.744
1m9t INENitric oxide synthase, inducible 1.14.13.39 0.744
1n83 CLRNuclear receptor ROR-alpha / 0.744
1o6q R17Squalene--hopene cyclase 4.2.1.129 0.744
1pj6 FOLDimethylglycine oxidase 1.5.3.10 0.744
1pq9 44BOxysterols receptor LXR-beta / 0.744
1pqc 444Oxysterols receptor LXR-beta / 0.744
1q20 PLOSulfotransferase family cytosolic 2B member 1 2.8.2.2 0.744
1qiw DPDCalmodulin / 0.744
1qjg EQUSteroid Delta-isomerase 5.3.3.1 0.744
1qti GNTAcetylcholinesterase 3.1.1.7 0.744
1qvt PRLHTH-type transcriptional regulator QacR / 0.744
1rpw DIDHTH-type transcriptional regulator QacR / 0.744
1rt1 MKCGag-Pol polyprotein 2.7.7.49 0.744
1rt4 UC1Gag-Pol polyprotein 2.7.7.49 0.744
1rt5 UC2Gag-Pol polyprotein 2.7.7.49 0.744
1s1t UC1Gag-Pol polyprotein 2.7.7.49 0.744
1s1v TNKGag-Pol polyprotein 2.7.7.49 0.744
1sej F89Bifunctional dihydrofolate reductase-thymidylate synthase / 0.744
1snu STUTyrosine-protein kinase ITK/TSK 2.7.10.2 0.744
1suo CPZCytochrome P450 2B4 1.14.14.1 0.744
1tkx GWBGag-Pol polyprotein 2.7.7.49 0.744
1tkz H16Gag-Pol polyprotein 2.7.7.49 0.744
1tvr TB9Gag-Pol polyprotein 2.7.7.49 0.744
1u0w STLChalcone synthase 2 2.3.1.74 0.744
1u65 CP0Acetylcholinesterase 3.1.1.7 0.744
1uym PU3Heat shock protein HSP 90-beta / 0.744
1vru AAPGag-Pol polyprotein 2.7.7.49 0.744
1vzd CB3Thymidylate synthase / 0.744
1w4l GL8Acetylcholinesterase 3.1.1.7 0.744
1w6j R71Lanosterol synthase 5.4.99.7 0.744
1w6r GNTAcetylcholinesterase 3.1.1.7 0.744
1w76 GNTAcetylcholinesterase 3.1.1.7 0.744
1wxy FRKAdenosine deaminase 3.5.4.4 0.744
1xk9 P34Exotoxin A 2.4.2.36 0.744
1xws BI1Serine/threonine-protein kinase pim-1 2.7.11.1 0.744
1yi4 ADNSerine/threonine-protein kinase pim-1 2.7.11.1 0.744
1ysw 43BApoptosis regulator Bcl-2 / 0.744
1z1f STLResveratrol synthase / 0.744
1zg3 2HIIsoflavone 4'-O-methyltransferase / 0.744
1zga HMKIsoflavone 4'-O-methyltransferase / 0.744
1zhw HC2Oxysterol-binding protein homolog 4 / 0.744
1zhz ERGOxysterol-binding protein homolog 4 / 0.744
1zz1 SHHHistone deacetylase-like amidohydrolase 3.5.1 0.744
2a8g GNGAvidin / 0.744
2acl L05Oxysterols receptor LXR-alpha / 0.744
2agv BHQSarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.6.3.8 0.744
2aot 2PMHistamine N-methyltransferase 2.1.1.8 0.744
2aov C2MHistamine N-methyltransferase 2.1.1.8 0.744
2azy CHDPhospholipase A2, major isoenzyme 3.1.1.4 0.744
2b00 GCHPhospholipase A2, major isoenzyme 3.1.1.4 0.744
2b5j 3ACGag-Pol polyprotein 2.7.7.49 0.744
2ban 357Gag-Pol polyprotein 2.7.7.49 0.744
2bfm TOPPteridine reductase 1 1.5.1.33 0.744
2bil BI1Serine/threonine-protein kinase pim-1 2.7.11.1 0.744
2bjf DXCCholoylglycine hydrolase 3.5.1.24 0.744
2c7x NRBCytochrome P450 monooxygenase PikC / 0.744
2cib CM6Lanosterol 14-alpha demethylase 1.14.13.70 0.744
2ckm AA7Acetylcholinesterase 3.1.1.7 0.744
2eau CZASarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.6.3.8 0.744
2fhk MFNFormylmethanofuran--tetrahydromethanopterin formyltransferase 2.3.1.101 0.744
2g44 T3OEstrogen receptor / 0.744
2gby BRNHTH-type transcriptional regulator QacR / 0.744
2giu FBREstrogen receptor beta / 0.744
2gm1 2AZKinesin-like protein KIF11 / 0.744
2gz8 F3FOrf1a polyprotein / 0.744
2hnz PC0Gag-Pol polyprotein 2.7.7.49 0.744
2hz4 4STTyrosine-protein kinase ABL1 2.7.10.2 0.744
2i80 G1LD-alanine--D-alanine ligase / 0.744
2ibz SMACytochrome b / 0.744
2ic3 HBYGag-Pol polyprotein 2.7.7.49 0.744
2j0k 4STFocal adhesion kinase 1 2.7.10.2 0.744
2j2i LY4Serine/threonine-protein kinase pim-1 2.7.11.1 0.744
2kot ANWProtein S100-A13 / 0.744
2o21 43BApoptosis regulator Bcl-2 / 0.744
2ocf ESTEstrogen receptor / 0.744
2ohv NHLGlutamate racemase / 0.744
2opb F21Phenylethanolamine N-methyltransferase 2.1.1.28 0.744
2pvh P19Casein kinase II subunit alpha 2.7.11.1 0.744
2q5y TYR_GLY_LEUNuclear pore complex protein Nup98-Nup96 / 0.744
2q6h CXXNa(+):neurotransmitter symporter (Snf family) / 0.744
2qei CXXNa(+):neurotransmitter symporter (Snf family) / 0.744
2r9k SGIBeta-galactoside-specific lectin 1 / 0.744
2rbe ZMGCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.744
2std CRPScytalone dehydratase 4.2.1.94 0.744
2uxp CLMHTH-type transcriptional regulator TtgR / 0.744
2v61 C18Amine oxidase [flavin-containing] B 1.4.3.4 0.744
2vcg S17Histone deacetylase-like amidohydrolase 3.5.1 0.744
2vg5 NNCGag-Pol polyprotein 2.7.7.49 0.744
2vg7 NNIGag-Pol polyprotein 2.7.7.49 0.744
2vq5 LDPS-norcoclaurine synthase / 0.744
2vuk P83Cellular tumor antigen p53 / 0.744
2w0b CMWLanosterol 14-alpha demethylase 1.14.13.70 0.744
2w4i VGAGlutamate racemase / 0.744
2w6c BM4Acetylcholinesterase 3.1.1.7 0.744
2whq HI6Acetylcholinesterase 3.1.1.7 0.744
2wu4 HBPAcetylcholinesterase 3.1.1.7 0.744
2xae 2XAKinesin-like protein KIF11 / 0.744
2xc5 OYJCoagulation factor X 3.4.21.6 0.744
2xiy XIYSerine/threonine-protein kinase pim-1 2.7.11.1 0.744
2xnv VU3Soluble acetylcholine receptor / 0.744
2xw1 9NVSerum albumin / 0.744
2xys SY9Soluble acetylcholine receptor / 0.744
2y3r TIRTamL / 0.744
2ycs NXPSerine/threonine-protein kinase Chk2 2.7.11.1 0.744
2yne YNEGlycylpeptide N-tetradecanoyltransferase / 0.744
2zdx P4A[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.744
3aba FLICytochrome P450 / 0.744
3acw 651Dehydrosqualene synthase / 0.744
3ar4 TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.6.3.8 0.744
3ar6 TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.6.3.8 0.744
3arq DM5Chitinase A / 0.744
3ayg HQONitric oxide reductase / 0.744
3bpt QUE3-hydroxyisobutyryl-CoA hydrolase, mitochondrial 3.1.2.4 0.744
3br2 DEQHTH-type transcriptional regulator QacR / 0.744
3br3 ETHTH-type transcriptional regulator QacR / 0.744
3c4e C4ESerine/threonine-protein kinase pim-1 2.7.11.1 0.744
3cgy RDCVirulence sensor histidine kinase PhoQ 2.7.13.3 0.744
3cho 4BGLeukotriene A-4 hydrolase 3.3.2.6 0.744
3clx X22E3 ubiquitin-protein ligase XIAP 6.3.2 0.744
3d27 W29Methionine aminopeptidase / 0.744
3dl9 V2HVitamin D 25-hydroxylase / 0.744
3dnd LL2cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.744
3dyq IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.744
3ej0 11XInorganic pyrophosphatase / 0.744
3exo 5MSBeta-secretase 1 3.4.23.46 0.744
3ey4 352Corticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.744
3fnh JPJEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.744
3foo PXXSoluble cytochrome b562 / 0.744
3ful 52DLeukotriene A-4 hydrolase 3.3.2.6 0.744
3gcm 5GPPolyribonucleotide nucleotidyltransferase / 0.744
3ggs 2FDPurine nucleoside phosphorylase 2.4.2.1 0.744
3gw9 VNILanosterol 14-alpha-demethylase / 0.744
3gwu SRENa(+):neurotransmitter symporter (Snf family) / 0.744
3hxe BD8Geranylgeranyl transferase type-2 subunit beta 2.5.1.60 0.744
3i64 DNA2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase / 0.744
3ibd CPZCytochrome P450 2B6 1.14.13 0.744
3il1 B5DGlutamate receptor 2 / 0.744
3inl BXBAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.744
3ipt EQUSteroid Delta-isomerase 5.3.3.1 0.744
3itu IBMcGMP-dependent 3',5'-cyclic phosphodiesterase 3.1.4.17 0.744
3iu9 T07Methionine aminopeptidase 2 / 0.744
3iw8 HIZMitogen-activated protein kinase 14 / 0.744
3jq8 DX3Pteridine reductase, putative / 0.744
3jx3 JI5Nitric oxide synthase, brain 1.14.13.39 0.744
3jx6 JI5Nitric oxide synthase, brain 1.14.13.39 0.744
3keg MREFMN-dependent NADH-azoreductase 1 / 0.744
3kyt HC2Nuclear receptor ROR-gamma / 0.744
3lal KRVGag-Pol polyprotein 2.7.7.49 0.744
3lam KRPGag-Pol polyprotein 2.7.7.49 0.744
3lpg Z78Beta-glucuronidase 3.2.1.31 0.744
3lzz GDPUncharacterized protein / 0.744
3m6g LO3Actin, alpha skeletal muscle / 0.744
3m8p 65BGag-Pol polyprotein 2.7.7.49 0.744
3mdm FJZCholesterol 24-hydroxylase / 0.744
3mj5 GRMReplicase polyprotein 1a 3.4.22 0.744
3mla JJZProbable nicotinate-nucleotide adenylyltransferase / 0.744
3mpe N2ACathepsin S 3.4.22.27 0.744
3my5 RFZCyclin-dependent kinase 2 2.7.11.22 0.744
3myu VIBHigh affinity transport system protein p37 / 0.744
3neg PYVAbscisic acid receptor PYL1 / 0.744
3njo PYVAbscisic acid receptor PYR1 / 0.744
3nlq JRRNitric oxide synthase, brain 1.14.13.39 0.744
3nly 3XCNitric oxide synthase, brain 1.14.13.39 0.744
3nny 59RNitric oxide synthase, brain 1.14.13.39 0.744
3nzk C90UDP-3-O-acyl-N-acetylglucosamine deacetylase / 0.744
3o73 O73Ribosyldihydronicotinamide dehydrogenase [quinone] / 0.744
3oht 1N1Mitogen-activated protein kinase / 0.744
3owy EQUSteroid Delta-isomerase 5.3.3.1 0.744
3p99 LNPLanosterol 14-alpha-demethylase / 0.744
3pah XDEPhenylalanine-4-hydroxylase 1.14.16.1 0.744
3pcf FHBProtocatechuate 3,4-dioxygenase beta chain 1.13.11.3 0.744
3pmu F7LEndothiapepsin 3.4.23.22 0.744
3psu LJGGag-Pol polyprotein 3.4.23.16 0.744
3pyy 3YYTyrosine-protein kinase ABL1 2.7.10.2 0.744
3qgd 26SGenome polyprotein 2.7.7.48 0.744
3qgf 46FGenome polyprotein 2.7.7.48 0.744
3qi4 IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.744
3rox TEPNAD(P)H-hydrate epimerase 5.1.99.6 0.744
3rqj Y2BNitric oxide synthase, brain 1.14.13.39 0.744
3s7b NH5N-lysine methyltransferase SMYD2 / 0.744
3sfh 1DIHistone deacetylase 8 3.5.1.98 0.744
3svp JK5Nitric oxide synthase, brain 1.14.13.39 0.744
3svq JK4Nitric oxide synthase, brain 1.14.13.39 0.744
3szf DCQSulfide-quinone reductase / 0.744
3tda PN0Cytochrome P450 2D6 / 0.744
3tdj 3TJGlutamate receptor 2 / 0.744
3tk3 CPZCytochrome P450 2B4 1.14.14.1 0.744
3tky N7I(Iso)eugenol O-methyltransferase 2.1.1.146 0.744
3u9n 09HSerine/threonine-protein kinase Chk1 2.7.11.1 0.744
3uft HW7Nitric oxide synthase, brain 1.14.13.39 0.744
3v1s 0LHStrictosidine synthase 4.3.3.2 0.744
3vev 0H4Glucokinase 2.7.1.2 0.744
3vgn FNNSteroid Delta-isomerase 5.3.3.1 0.744
3wsb RWZFarnesyltransferase, putative / 0.744
3zr7 OR8Progesterone receptor / 0.744
3zra ORBProgesterone receptor / 0.744
3zrb OR8Progesterone receptor / 0.744
3zrb ORCProgesterone receptor / 0.744
4a5y G7XKinesin-like protein KIF11 / 0.744
4a9r RU5Serine/threonine-protein kinase Chk2 2.7.11.1 0.744
4as7 6LXKinesin-like protein KIF11 / 0.744
4awg CI3Polymerase acidic protein / 0.744
4b6u M7GEukaryotic translation initiation factor 4E type 3 / 0.744
4b71 DJLGenome polyprotein 3.4.21.98 0.744
4b76 PW1Genome polyprotein 3.4.21.98 0.744
4b7z Q4QAcetylcholinesterase 3.1.1.7 0.744
4bbh YBNGlycylpeptide N-tetradecanoyltransferase / 0.744
4bqg 50QHeat shock protein HSP 90-alpha / 0.744
4dij BLFE3 ubiquitin-protein ligase Mdm2 6.3.2 0.744
4dkp 0LLEnvelope glycoprotein gp160 / 0.744
4dkv 0KWEnvelope glycoprotein gp160 / 0.744
4dlj 6RGMitogen-activated protein kinase 14 / 0.744
4dvq 1CACytochrome P450 11B2, mitochondrial 1.14.15.4 0.744
4e0u 0MVCyclic dipeptide N-prenyltransferase / 0.744
4e6a 0O9Mitogen-activated protein kinase 14 / 0.744
4e70 N7IConiferyl alcohol 9-O-methyltransferase / 0.744
4ea0 651Dehydrosqualene synthase / 0.744
4eh3 IRGMitogen-activated protein kinase 14 / 0.744
4eh6 IRGMitogen-activated protein kinase 14 / 0.744
4ejv LCLTranscriptional regulator TcaR / 0.744
4fox D16Thymidylate synthase ThyA / 0.744
4fxy 0W2Neurolysin, mitochondrial 3.4.24.16 0.744
4g09 0VDHistidinol dehydrogenase / 0.744
4g3j VNTLanosterol 14-alpha-demethylase / 0.744
4g48 PZBMycocyclosin synthase 1.14.21.9 0.744
4g7g VFVLanosterol 14-alpha-demethylase / 0.744
4guk P2GNeuronal calcium sensor 1 / 0.744
4hdr DMDNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase / 0.744
4hdr DMDArsB / 0.744
4hfn CIY2-alkenal reductase (NADP(+)-dependent) / 0.744
4hmb PZZPhospholipase A2 VRV-PL-VIIIa / 0.744
4hz5 19YDNA topoisomerase 4 subunit B / 0.744
4iqq D16Thymidylate synthase / 0.744
4iyg 1HUStrictosidine synthase 4.3.3.2 0.744
4j6d TESCytochrome P450 monooxygenase / 0.744
4j7d I31E3 ubiquitin-protein ligase Mdm2 6.3.2 0.744
4jlj 1NMDeoxycytidine kinase 2.7.1.74 0.744
4jr5 1LSNicotinamide phosphoribosyltransferase 2.4.2.12 0.744
4k3n 1OTM17 leucyl aminopeptidase / 0.744
4kfo 1QSNicotinamide phosphoribosyltransferase 2.4.2.12 0.744
4lg5 A1OAbscisic acid receptor PYL2 / 0.744
4lm4 JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 3.1.4.17 0.744
4lmu QUESerine/threonine-protein kinase pim-1 2.7.11.1 0.744
4loc BTNPyruvate carboxylase / 0.744
4lxj LANLanosterol 14-alpha demethylase 1.14.13.70 0.744
4m0f 1YKAcetylcholinesterase 3.1.1.7 0.744
4m48 21BSodium-dependent dopamine transporter / 0.744
4man 1Y1Apoptosis regulator Bcl-2 / 0.744
4mme 29QNa(+):neurotransmitter symporter (Snf family) / 0.744
4n6h EJ4Delta-type opioid receptor / 0.744
4nbb 9CATerminal oxygenase component of carbazole / 0.744
4nbh 9CATerminal oxygenase component of carbazole / 0.744
4ng5 PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
4nh9 2LCEndoplasmin / 0.744
4nkv AERSteroid 17-alpha-hydroxylase/17,20 lyase / 0.744
4o78 SAVBromodomain-containing protein 4 / 0.744
4qem HC4Phospholipase A2 VRV-PL-VIIIa / 0.744
4qer STLPhospholipase A2 VRV-PL-VIIIa / 0.744
4qjq OTRLactoperoxidase / 0.744
4r20 AERCytochrome P450 family 17 polypeptide 2 / 0.744
4rel KMPGlycosyltransferase / 0.744
4rgs V55Repressor protein / 0.744
4ryv ZEAProtein LlR18A / 0.744
4tuv CPZCytochrome P450 119 1.14 0.744
4u95 MIYMultidrug efflux pump subunit AcrB / 0.744
4xoq F42Coenzyme F420:L-glutamate ligase / 0.744
4xp4 COCSodium-dependent dopamine transporter / 0.744
5a4w QCTGlutathione S-transferase F2 2.5.1.18 0.744
5alu HD2Bifunctional epoxide hydrolase 2 3.1.3.76 0.744
5c8a 5ADProbable transcriptional regulator / 0.744
5cds PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
5cdt PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
5fli QUEQuercetinase QueD / 0.744
5flj QUEQuercetinase QueD / 0.744
5kj1 PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
5kjc PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
6std MS2Scytalone dehydratase 4.2.1.94 0.744
7std CRPScytalone dehydratase 4.2.1.94 0.744
5xra CLRCannabinoid receptor 1 / 0.744
5l7d CLRSmoothened homolog / 0.744
5dhh DGWNociceptin receptor / 0.744
5dhg DGVNociceptin receptor / 0.744
3pbl ETQD(3) dopamine receptor / 0.744
2cgw 3C3Serine/threonine-protein kinase Chk1 2.7.11.1 0.713
4uya AGSMitogen-activated protein kinase kinase kinase 21 2.7.11.25 0.678
2ydi YDISerine/threonine-protein kinase Chk1 2.7.11.1 0.677
3pjc PJCTyrosine-protein kinase JAK3 2.7.10.2 0.676
4c36 ZO9cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.676
3cd3 STUTyrosine-protein kinase Fes/Fps 2.7.10.2 0.674
2wmq ZYQSerine/threonine-protein kinase Chk1 2.7.11.1 0.673
2pbz ATPUncharacterized protein / 0.672
4b2w BZ0Glucose-1-phosphate thymidylyltransferase / 0.672
4l52 1ULMitogen-activated protein kinase kinase kinase 7 2.7.11.25 0.672
2wgj VGHHepatocyte growth factor receptor 2.7.10.1 0.671
3vs2 VSBTyrosine-protein kinase HCK 2.7.10.2 0.671
3vs4 VSFTyrosine-protein kinase HCK 2.7.10.2 0.671
1pwl BFIAldose reductase 1.1.1.21 0.670
2x8e X8ESerine/threonine-protein kinase Chk1 2.7.11.1 0.670
2yfx VGHALK tyrosine kinase receptor 2.7.10.1 0.670
3hdm MMGSerine/threonine-protein kinase Sgk1 2.7.11.1 0.670
3vs0 VS0Tyrosine-protein kinase HCK 2.7.10.2 0.670
4ans VGHALK tyrosine kinase receptor 2.7.10.1 0.670
4ccb OFGALK tyrosine kinase receptor 2.7.10.1 0.670
4dfn 0K1Tyrosine-protein kinase SYK 2.7.10.2 0.670
5aab VGHALK tyrosine kinase receptor 2.7.10.1 0.670
2pvr ANPCasein kinase II subunit alpha 2.7.11.1 0.669
2xp2 VGHALK tyrosine kinase receptor 2.7.10.1 0.669
3zm9 QMQCholine kinase alpha 2.7.1.32 0.669
4anq VGHALK tyrosine kinase receptor 2.7.10.1 0.669
4b4b GJBGlucose-1-phosphate thymidylyltransferase / 0.669
4c2w ANPAurora kinase B-A 2.7.11.1 0.669
5aac VGHALK tyrosine kinase receptor 2.7.10.1 0.669
2e9u A25Serine/threonine-protein kinase Chk1 2.7.11.1 0.668
3ac2 KSETyrosine-protein kinase Lck 2.7.10.2 0.668
3zew STUEphrin type-B receptor 4 2.7.10.1 0.668
4fr4 STUSerine/threonine-protein kinase 32A 2.7.11.1 0.668
4mvf STUCalcium-dependent protein kinase 2 2.7.11.1 0.668
4acg 6LQGlycogen synthase kinase-3 beta 2.7.11.26 0.667
4dca ADPAminoglycoside phosphotransferase / 0.667
4dgg I76Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.667
4hnf 16WCasein kinase I isoform delta 2.7.11.1 0.667
4lgg VGGProto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.667
4xhg ADPUncharacterized protein / 0.667
2duv 371Cyclin-dependent kinase 2 2.7.11.22 0.666
2itx ANPEpidermal growth factor receptor 2.7.10.1 0.666
2ow3 BIMGlycogen synthase kinase-3 beta 2.7.11.26 0.666
2xik J60Serine/threonine-protein kinase 25 2.7.11.1 0.666
3hmv HBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B 3.1.4.53 0.666
4gu9 4GUFocal adhesion kinase 1 2.7.10.2 0.666
5d3f FSC14-3-3 protein zeta/delta / 0.666
1ztf XYARIO-type serine/threonine-protein kinase Rio1 2.7.11.1 0.665
2i0e PDSProtein kinase C beta type 2.7.11.13 0.665
3h4g FIDAlcohol dehydrogenase [NADP(+)] 1.1.1.2 0.665
3ncg BK1Calmodulin-domain protein kinase 1, putative / 0.665
3nuu JOZ3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.665
3sd0 TSKGlycogen synthase kinase-3 beta 2.7.11.26 0.665
4bid IE8Mitogen-activated protein kinase kinase kinase 5 2.7.11.25 0.665
4e4m 0NHTyrosine-protein kinase JAK2 / 0.665
2buj STUSerine/threonine-protein kinase 16 / 0.664
3b2t M33Fibroblast growth factor receptor 2 / 0.664
4ach KDIGlycogen synthase kinase-3 beta 2.7.11.26 0.664
4ckj ADNProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.664
4ft3 H1KSerine/threonine-protein kinase Chk1 2.7.11.1 0.664
4id7 1G0Activated CDC42 kinase 1 / 0.664
4j71 1JXGlycogen synthase kinase-3 beta 2.7.11.26 0.664
4lgh 0JNProto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.664
1c1c 612Gag-Pol polyprotein 2.7.7.49 0.663
1q3d STUGlycogen synthase kinase-3 beta 2.7.11.26 0.663
2pdk SBIAldose reductase 1.1.1.21 0.663
3ac1 KZITyrosine-protein kinase Lck 2.7.10.2 0.663
3lcd BDYMacrophage colony-stimulating factor 1 receptor 2.7.10.1 0.663
3lxk MI1Tyrosine-protein kinase JAK3 2.7.10.2 0.663
3mtf A3FActivin receptor type-1 2.7.11.30 0.663
3mvj XFEcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.663
3vs7 KS1Tyrosine-protein kinase HCK 2.7.10.2 0.663
4ga8 SBIAldo-keto reductase family 1 member B10 1.1.1 0.663
4i0s 1B5Tyrosine-protein kinase SYK 2.7.10.2 0.663
1h1r 6CPCyclin-dependent kinase 2 2.7.11.22 0.662
2uw0 GVKcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.662
3py0 SU9Cyclin-dependent kinase 2 2.7.11.22 0.662
4cki ADNProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.662
4dt8 ADNAPH(2'')-Id / 0.662
4hvh 19RTyrosine-protein kinase JAK3 2.7.10.2 0.662
4joa 3DKALK tyrosine kinase receptor 2.7.10.1 0.662
1qcf PP1Tyrosine-protein kinase HCK 2.7.10.2 0.661
1qpe PP2Tyrosine-protein kinase Lck 2.7.10.2 0.661
2jam J60Calcium/calmodulin-dependent protein kinase type 1G 2.7.11.17 0.661
3ckx STUSerine/threonine-protein kinase 24 2.7.11.1 0.661
3g0f B49Mast/stem cell growth factor receptor Kit 2.7.10.1 0.661
3lct ADPALK tyrosine kinase receptor 2.7.10.1 0.661
3uim ANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 2.7.10.1 0.661
3zc6 VFCTyrosine-protein kinase JAK3 2.7.10.2 0.661
4f08 1RSTyrosine-protein kinase JAK2 / 0.661
4i0r 1B4Tyrosine-protein kinase SYK 2.7.10.2 0.661
4ih8 B43Calmodulin-domain protein kinase 1 / 0.661
1acj THAAcetylcholinesterase 3.1.1.7 0.660
1c3x 8IGPurine nucleoside phosphorylase 2.4.2.1 0.660
1d3p BT3Prothrombin 3.4.21.5 0.660
1h46 RNPGlucanase / 0.660
1jt6 DEQHTH-type transcriptional regulator QacR / 0.660
1lqd CMICoagulation factor X 3.4.21.6 0.660
1q0r AKTAclacinomycin methylesterase RdmC 3.1.1.95 0.660
1q0z AKAAclacinomycin methylesterase RdmC 3.1.1.95 0.660
1tvv CB3Thymidylate synthase / 0.660
1yho TRRDihydrofolate reductase 1.5.1.3 0.660
1zzq DP9Nitric oxide synthase, brain 1.14.13.39 0.660
1zzr DP9Nitric oxide synthase, brain 1.14.13.39 0.660
2c6h PXICytochrome P450 monooxygenase PikC / 0.660
2cd8 PXICytochrome P450 monooxygenase PikC / 0.660
2cjp VPREpoxide hydrolase / 0.660
2g72 F21Phenylethanolamine N-methyltransferase 2.1.1.28 0.660
2jf0 HBPAcetylcholinesterase 3.1.1.7 0.660
2oae AILDipeptidyl peptidase 4 / 0.660
2pjl 047Steroid hormone receptor ERR1 / 0.660
2pks G44Prothrombin 3.4.21.5 0.660
2qjp ANJCytochrome b / 0.660
2qmz LDPRibosyldihydronicotinamide dehydrogenase [quinone] / 0.660
2v57 PRLTetR family transcriptional regulator / 0.660
2v5z SAGAmine oxidase [flavin-containing] B 1.4.3.4 0.660
2va6 H24Beta-secretase 1 3.4.23.46 0.660
2va7 C27Beta-secretase 1 3.4.23.46 0.660
2vzm NRBCytochrome P450 monooxygenase PikC / 0.660
2wd8 VGFPteridine reductase / 0.660
2wog ZZDKinesin-like protein KIF11 / 0.660
2xk7 30ESerine/threonine-protein kinase Nek2 2.7.11.1 0.660
2ze2 T27Gag-Pol polyprotein 2.7.7.49 0.660
2zv9 PP2Tyrosine-protein kinase Lyn 2.7.10.2 0.660
3bc4 LLGGag-Pol polyprotein 3.4.23.16 0.660
3bt9 DEQHTH-type transcriptional regulator QacR / 0.660
3btj DEQHTH-type transcriptional regulator QacR / 0.660
3cxw 7CPSerine/threonine-protein kinase pim-1 2.7.11.1 0.660
3cy2 MB9Serine/threonine-protein kinase pim-1 2.7.11.1 0.660
3dg8 RJ6Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.660
3fu5 492Leukotriene A-4 hydrolase 3.3.2.6 0.660
3fun 798Leukotriene A-4 hydrolase 3.3.2.6 0.660
3gn2 AX8Pteridine reductase / 0.660
3iu8 T03Methionine aminopeptidase 2 / 0.660
3ken ZZDKinesin-like protein KIF11 / 0.660
3kjm 245Cytokinin dehydrogenase 1 1.5.99.12 0.660
3ko0 TFPProtein S100-A4 / 0.660
3l5b BDOBeta-secretase 1 3.4.23.46 0.660
3m0w P77Protein S100-A4 / 0.660
3pgi F41Endothiapepsin 3.4.23.22 0.660
3pld F90Endothiapepsin 3.4.23.22 0.660
3pll F06Endothiapepsin 3.4.23.22 0.660
3qai XNNKetohexokinase / 0.660
3t40 3RGIndole-3-glycerol phosphate synthase 4.1.1.48 0.660
3ufl 508Beta-secretase 1 3.4.23.46 0.660
3ufv HW9Nitric oxide synthase, brain 1.14.13.39 0.660
3wb4 0B3Beta-secretase 1 3.4.23.46 0.660
3zls 92PDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.660
4a51 DQ8Kinesin-like protein KIF11 / 0.660
4b12 C23Glycylpeptide N-tetradecanoyltransferase / 0.660
4bbg V02Kinesin-like protein KIF11 / 0.660
4c59 FEFCyclin-G-associated kinase 2.7.11.1 0.660
4cfn JYMCyclin-dependent kinase 2 2.7.11.22 0.660
4da5 0H7Choline kinase alpha 2.7.1.32 0.660
4eh4 IRGMitogen-activated protein kinase 14 / 0.660
4eip K2CPutative FAD-monooxygenase / 0.660
4fic 0ULProto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.660
4fog C2FThymidylate synthase ThyA / 0.660
4ha5 13WBeta-secretase 1 3.4.23.46 0.660
4jhz 1KVBeta-glucuronidase 3.2.1.31 0.660
4jq7 KJQEpidermal growth factor receptor 2.7.10.1 0.660
4k11 0J9Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.660
4kfp 1R7Nicotinamide phosphoribosyltransferase 2.4.2.12 0.660
4lm5 Q17Serine/threonine-protein kinase pim-1 2.7.11.1 0.660
4m6p 20RNicotinamide phosphoribosyltransferase 2.4.2.12 0.660
4mm4 8PRNa(+):neurotransmitter symporter (Snf family) / 0.660
4mmd 29ENa(+):neurotransmitter symporter (Snf family) / 0.660
4o95 245Cytokinin dehydrogenase 4 / 0.660
4oal 245Cytokinin dehydrogenase 4 / 0.660
4uco IWHDNA ligase / 0.660
4y35 F90Endothiapepsin 3.4.23.22 0.660
4y3r F06Endothiapepsin 3.4.23.22 0.660
4y4j LNREndothiapepsin 3.4.23.22 0.660
5d7p OCZNAD-dependent protein deacetylase sirtuin-2 3.5.1 0.660
1m9k 7NINitric oxide synthase, endothelial 1.14.13.39 0.659
2ivv PP1Proto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.659
2wmt ZYTSerine/threonine-protein kinase Chk1 2.7.11.1 0.659
2wmu ZYUSerine/threonine-protein kinase Chk1 2.7.11.1 0.659
3vry B43Tyrosine-protein kinase HCK 2.7.10.2 0.659
3vs5 VSGTyrosine-protein kinase HCK 2.7.10.2 0.659
4btm F8ETau-tubulin kinase 1 2.7.11.1 0.659
4e6d 0NUTyrosine-protein kinase JAK2 / 0.659
4idt T28Mitogen-activated protein kinase kinase kinase 14 2.7.11.25 0.659
4uqs INENitric oxide synthase oxygenase 1.14.13.165 0.659
2be2 R22Gag-Pol polyprotein 2.7.7.49 0.658
2qhm 7CSSerine/threonine-protein kinase Chk1 2.7.11.1 0.658
2x2k X2KProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.658
3pxk PXKFocal adhesion kinase 1 2.7.10.2 0.658
3sa0 NRAMitogen-activated protein kinase 1 2.7.11.24 0.658
4hvi 19STyrosine-protein kinase JAK3 2.7.10.2 0.658
4i5c C5ITyrosine-protein kinase JAK1 / 0.658
3d76 NBBPheromone-binding protein ASP1 / 0.657
4hni 16WCasein kinase I isoform epsilon 2.7.11.1 0.657
4twp AXITyrosine-protein kinase ABL1 2.7.10.2 0.657
5f0a 1FBcGMP-dependent protein kinase, putative / 0.657
1e1v CMGCyclin-dependent kinase 2 2.7.11.22 0.656
2wqb QQ1Angiopoietin-1 receptor 2.7.10.1 0.656
2x2m X2MProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.656
3hzt J60Calmodulin-like domain protein kinase isoform 3 / 0.656
3cqu CQURAC-alpha serine/threonine-protein kinase 2.7.11.1 0.655
1m9r INENitric oxide synthase, endothelial 1.14.13.39 0.654
4kbc 1QJCasein kinase I isoform delta 2.7.11.1 0.654
3r4n FU5Heat shock protein HSP 90-alpha / 0.653
1ah0 SBIAldose reductase 1.1.1.21 0.652
1zw9 H64ATP-dependent molecular chaperone HSP82 / 0.652
2qfo A13Heat shock protein HSP 90-alpha / 0.652
1uyd PU8Heat shock protein HSP 90-alpha / 0.650
1uyf PU1Heat shock protein HSP 90-alpha / 0.650
2h55 DZ8Heat shock protein HSP 90-alpha / 0.650
4acd GR9Glycogen synthase kinase-3 beta 2.7.11.26 0.650
4egi B2JHeat shock protein HSP 90-alpha / 0.650
4gt3 ATPMitogen-activated protein kinase 1 2.7.11.24 0.650