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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2a7r 5GP GMP reductase 2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2a7r 5GPGMP reductase 2 / 0.886
2bwg 5GPGMP reductase 1 / 0.732
2cu0 XMPInosine-5'-monophosphate dehydrogenase / 0.713
4qq3 XMPInosine-5'-monophosphate dehydrogenase / 0.679
1me7 RVPInosine-5'-monophosphate dehydrogenase / 0.673
1nf7 RVPInosine-5'-monophosphate dehydrogenase 2 / 0.670
4zqm XMPInosine-5'-monophosphate dehydrogenase / 0.661
1me8 RVPInosine-5'-monophosphate dehydrogenase / 0.657