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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1zap A70 Candidapepsin-2 3.4.23.24

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1zap A70Candidapepsin-2 3.4.23.24 1.351
1eag A70Candidapepsin-2 3.4.23.24 1.036
1od1 0QSEndothiapepsin 3.4.23.22 0.762
2g94 ZPQBeta-secretase 1 3.4.23.46 0.758
3k5d XLIBeta-secretase 1 3.4.23.46 0.757
1e82 M90Endothiapepsin 3.4.23.22 0.741
2jjj 0QSEndothiapepsin 3.4.23.22 0.730
1e81 M91Endothiapepsin 3.4.23.22 0.727
3k5f AYHBeta-secretase 1 3.4.23.46 0.726
2jji 0QSEndothiapepsin 3.4.23.22 0.725
2f3e AXQBeta-secretase 1 3.4.23.46 0.719
1rne C60Renin 3.4.23.15 0.708
2p4j 23IBeta-secretase 1 3.4.23.46 0.706
3duy AFJBeta-secretase 1 3.4.23.46 0.706
3own 3OWRenin 3.4.23.15 0.706
1e80 0GQEndothiapepsin 3.4.23.22 0.702
3dv1 AR9Beta-secretase 1 3.4.23.46 0.696
2hiz LIJBeta-secretase 1 3.4.23.46 0.685
1qrp HH0Pepsin A-4 3.4.23.1 0.680
2iqg F2IBeta-secretase 1 3.4.23.46 0.679
1gvt 2ZSEndothiapepsin 3.4.23.22 0.676
1ppk IVVPenicillopepsin-1 3.4.23.20 0.675
1gvw 0EMEndothiapepsin 3.4.23.22 0.674
3i25 MV7Beta-secretase 1 3.4.23.46 0.671
1w6h TITPlasmepsin-2 3.4.23.39 0.665
1ppl 1Z7Penicillopepsin-1 3.4.23.20 0.659
3q70 RITCandidapepsin-2 3.4.23.24 0.659
1psa 0ZLPepsin A 3.4.23.1 0.658
3ixk 929Beta-secretase 1 3.4.23.46 0.656
2fdp FRPBeta-secretase 1 3.4.23.46 0.651
2hm1 LIQBeta-secretase 1 3.4.23.46 0.651