Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1wuq 8GT GTP cyclohydrolase 1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1wuq 8GTGTP cyclohydrolase 1 / 1.263
1wur 8DGGTP cyclohydrolase 1 / 1.198
1a8r GTPGTP cyclohydrolase 1 3.5.4.16 1.011
1a9c GTPGTP cyclohydrolase 1 3.5.4.16 0.815
1n3r GTPGTP cyclohydrolase 1 3.5.4.16 0.797
1n3s GTPGTP cyclohydrolase 1 3.5.4.16 0.795
4du6 GTPGTP cyclohydrolase 1 / 0.761
1lqu NDPNADPH-ferredoxin reductase FprA 1.18.1.2 0.675
5f1c ATPUncharacterized protein / 0.671
3inv NDPBifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.662
4m5p FMNNADPH dehydrogenase / 0.661
2ifa FMNUncharacterized protein / 0.660
2q0l NAPThioredoxin reductase 1.8.1.9 0.658
1fnd A2PFerredoxin--NADP reductase, chloroplastic 1.18.1.2 0.657
1mdt APUDiphtheria toxin / 0.657
3tjl FMNNADPH dehydrogenase / 0.657
4l03 NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.654
4nke IPEFarnesyl pyrophosphate synthase 2.5.1.10 0.653
2r2n KYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2.6.1.39 0.652