Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1vzq SHY Prothrombin 3.4.21.5

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1vzq SHYProthrombin 3.4.21.5 1.053
1oyt FSNProthrombin 3.4.21.5 0.931
2cf8 ESHProthrombin 3.4.21.5 0.916
1ype UIPProthrombin 3.4.21.5 0.890
2cn0 F25Prothrombin 3.4.21.5 0.886
1ypj UIBProthrombin 3.4.21.5 0.880
2cf9 348Prothrombin 3.4.21.5 0.838
1ypg UIRProthrombin 3.4.21.5 0.827
2znk 31UProthrombin 3.4.21.5 0.773
2bok 784Coagulation factor X 3.4.21.6 0.771
4ax9 N5NProthrombin 3.4.21.5 0.761
2ziq 26UProthrombin 3.4.21.5 0.760
4ayy 9MXProthrombin 3.4.21.5 0.760
4ayv 9MQProthrombin 3.4.21.5 0.741
1k21 IGNProthrombin 3.4.21.5 0.739
1d4p BPPProthrombin 3.4.21.5 0.728
2zi2 24UProthrombin 3.4.21.5 0.728
7kme ACE_0BN_CHG_PRRProthrombin 3.4.21.5 0.724
3biv 11UProthrombin 3.4.21.5 0.723
4baq M4ZProthrombin 3.4.21.5 0.723
3hat GLY_VAL_ARG_RNGProthrombin 3.4.21.5 0.722
1ypm RA4Prothrombin 3.4.21.5 0.720
2zhf 49UProthrombin 3.4.21.5 0.720
1ghv 120Prothrombin 3.4.21.5 0.718
2gde SN3Prothrombin 3.4.21.5 0.718
1k22 MELProthrombin 3.4.21.5 0.717
1ypk CCRProthrombin 3.4.21.5 0.711
2zhe 13UProthrombin 3.4.21.5 0.711
1ypl RA8Prothrombin 3.4.21.5 0.709
2a2x NA9Prothrombin 3.4.21.5 0.708
3plp BBACationic trypsin 3.4.21.4 0.705
2zfq 45UProthrombin 3.4.21.5 0.699
1riw OSCProthrombin 3.4.21.5 0.698
2pks G44Prothrombin 3.4.21.5 0.698
3v0x ANHCationic trypsin 3.4.21.4 0.698
2zda 32UProthrombin 3.4.21.5 0.696
2anm CDOProthrombin 3.4.21.5 0.691
4fud 6UPUrokinase-type plasminogen activator 3.4.21.73 0.691
2zhw 12UProthrombin 3.4.21.5 0.689
2zgx 29UProthrombin 3.4.21.5 0.688
5cmx 0G6Prothrombin 3.4.21.5 0.687
1lpk CBBCoagulation factor X 3.4.21.6 0.683
1ae8 AZLProthrombin 3.4.21.5 0.679
1nzq 162Prothrombin 3.4.21.5 0.679
2v3h I25Prothrombin 3.4.21.5 0.679
2zg0 50UProthrombin 3.4.21.5 0.677
3utu 1TSProthrombin 3.4.21.5 0.675
1kts C24Prothrombin 3.4.21.5 0.672
1owe 675Urokinase-type plasminogen activator 3.4.21.73 0.668
2v3o I26Prothrombin 3.4.21.5 0.666
4az2 9MUProthrombin 3.4.21.5 0.665
2bdy UNBProthrombin 3.4.21.5 0.664
4bam MM9Prothrombin 3.4.21.5 0.664
4ban M6SProthrombin 3.4.21.5 0.661
1wqv PSMCoagulation factor VII 3.4.21.21 0.660
4bao MVFProthrombin 3.4.21.5 0.659
1c4v IH2Prothrombin 3.4.21.5 0.657
1vja 7INUrokinase-type plasminogen activator 3.4.21.73 0.656
4ne0 ZZUHydroxylase / 0.656
1f92 UKPUrokinase-type plasminogen activator 3.4.21.73 0.655
1z71 L17Prothrombin 3.4.21.5 0.653
4fub 4UPUrokinase-type plasminogen activator 3.4.21.73 0.653