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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1vq1 SAM Release factor glutamine methyltransferase 2.1.1.297

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1vq1 SAMRelease factor glutamine methyltransferase 2.1.1.297 0.888
1nv9 SAHRelease factor glutamine methyltransferase 2.1.1.297 0.710
4m37 SAHProtein arginine N-methyltransferase 7 2.1.1 0.702
1sg9 SAMRelease factor glutamine methyltransferase 2.1.1.297 0.701
1nv8 SAMRelease factor glutamine methyltransferase 2.1.1.297 0.696
3mte SAM16S rRNA (adenine(1408)-N(1))-methyltransferase 2.1.1.180 0.677
3dmh SAMProbable ribosomal RNA small subunit methyltransferase / 0.668
3q87 SAMN6 ADENINE SPECIFIC DNA METHYLASE (METHYLTRANSFERASE SUPERFAMILY) / 0.662
3orh SAHGuanidinoacetate N-methyltransferase 2.1.1.2 0.658
5bxy SAHPutative RNA methylase family UPF0020 / 0.658
4dcm SAMRibosomal RNA large subunit methyltransferase G 2.1.1.174 0.656
4qnu GEKtRNA U34 carboxymethyltransferase / 0.653
3pb3 SAH16S rRNA (adenine(1408)-N(1))-methyltransferase 2.1.1.180 0.651
2zbp SAMRibosomal protein L11 methyltransferase 2.1.1 0.650
3wst SAHProtein arginine N-methyltransferase 7 2.1.1 0.650