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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1t5z DHT Androgen receptor

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1t5z DHTAndrogen receptor / 1.163
2pio DHTAndrogen receptor / 1.144
1t7r DHTAndrogen receptor / 1.131
1t74 DHTAndrogen receptor / 1.130
2pit DHTAndrogen receptor / 1.130
1t7f DHTAndrogen receptor / 1.117
2pip DHTAndrogen receptor / 1.111
4oez DHTAndrogen receptor / 1.107
1t76 DHTAndrogen receptor / 1.103
1t73 DHTAndrogen receptor / 1.102
1t79 DHTAndrogen receptor / 1.097
1t65 DHTAndrogen receptor / 1.093
4oea DHTAndrogen receptor / 1.085
1t7m DHTAndrogen receptor / 1.083
4oey DHTAndrogen receptor / 1.080
1t7t DHTAndrogen receptor / 1.077
2ama DHTAndrogen receptor / 1.077
4ofr DHTAndrogen receptor / 1.069
2piw DHTAndrogen receptor / 1.066
2pkl DHTAndrogen receptor / 1.064
2z4j DHTAndrogen receptor / 1.060
2piv DHTAndrogen receptor / 1.058
2piu DHTAndrogen receptor / 1.054
4ofu DHTAndrogen receptor / 1.054
2pix DHTAndrogen receptor / 1.050
2qpy DHTAndrogen receptor / 1.041
4oed DHTAndrogen receptor / 1.029
2piq DHTAndrogen receptor / 1.028
2ylp TESAndrogen receptor / 0.991
1xj7 DHTAndrogen receptor / 0.981
2pir DHTAndrogen receptor / 0.979
2q7l TESAndrogen receptor / 0.958
4hlw TESAndrogen receptor / 0.954
2q7k TESAndrogen receptor / 0.952
2pnu ENMAndrogen receptor / 0.926
2q7i TESAndrogen receptor / 0.870
2ao6 R18Androgen receptor / 0.819
1t63 DHTAndrogen receptor / 0.797
1xow R18Androgen receptor / 0.776
4e5l DBHPolymerase acidic protein / 0.768
2ylq TESAndrogen receptor / 0.759
2amb 17HAndrogen receptor / 0.744
1gs4 ZK5Androgen receptor / 0.739
1xq3 R18Androgen receptor / 0.737
1i5r HYCEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.721
2q7j TESAndrogen receptor / 0.716
1lho AOMSex hormone-binding globulin / 0.711
1qyw 5SDEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.709
2am9 TESAndrogen receptor / 0.698
3uzz ASD3-oxo-5-beta-steroid 4-dehydrogenase / 0.694
1y9r 1CAMineralocorticoid receptor / 0.686
3nhx ASDSteroid Delta-isomerase 5.3.3.1 0.685
3uzx AOM3-oxo-5-beta-steroid 4-dehydrogenase / 0.682
1g50 ESTEstrogen receptor / 0.680
3g1r FIT3-oxo-5-beta-steroid 4-dehydrogenase / 0.680
4qe6 JN3Bile acid receptor / 0.680
2d09 FLVBiflaviolin synthase CYP158A2 / 0.679
1yb1 AOIEstradiol 17-beta-dehydrogenase 11 1.1.1.62 0.678
4at2 ASDPossible succinate dehydrogenase / 0.672
1jtv TESEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.670
1xu7 CPSCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.668
3w5t LHPVitamin D3 receptor / 0.667
4q0a 4OAVitamin D3 receptor A / 0.666
1xf0 ASDAldo-keto reductase family 1 member C3 / 0.665
4ple CPSNuclear receptor subfamily 5 group A member 2 / 0.665
1n83 CLRNuclear receptor ROR-alpha / 0.664
3iw1 ASDSteroid C26-monooxygenase 1.14.13.141 0.664
1lri CLRBeta-elicitin cryptogein / 0.663
4k7a DHTAndrogen receptor / 0.662
3bej MUFBile acid receptor / 0.661
1sqn NDRProgesterone receptor / 0.660
3f3y 4OABile salt sulfotransferase 2.8.2.14 0.660
1coy ANDCholesterol oxidase 1.1.3.6 0.657
2ylo TESAndrogen receptor / 0.654
2lba CHOFatty acid binding protein 6 / 0.653
1p8d CO1Oxysterols receptor LXR-beta / 0.651
3uzx AOX3-oxo-5-beta-steroid 4-dehydrogenase / 0.651
3cmf PDN3-oxo-5-beta-steroid 4-dehydrogenase / 0.650
5hyr ESTEstrogen receptor / 0.650