Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1oiq HDU Cyclin-dependent kinase 2 2.7.11.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1oiq HDUCyclin-dependent kinase 2 2.7.11.22 0.824
1oit HDTCyclin-dependent kinase 2 2.7.11.22 0.714
1pxo CK7Cyclin-dependent kinase 2 2.7.11.22 0.703
3nup 3NUCyclin-dependent kinase 6 2.7.11.22 0.702
2vv9 IM9Cyclin-dependent kinase 2 2.7.11.22 0.675
1pxp CK8Cyclin-dependent kinase 2 2.7.11.22 0.671
3igg EFQCyclin-dependent kinase 2 2.7.11.22 0.667
2w06 FRVCyclin-dependent kinase 2 2.7.11.22 0.665
2xmy CDKCyclin-dependent kinase 2 2.7.11.22 0.661
2wxv WXVCyclin-dependent kinase 2 2.7.11.22 0.660
2b55 D31Cyclin-dependent kinase 2 2.7.11.22 0.658
4dit 0KDGlycogen synthase kinase-3 beta 2.7.11.26 0.657
4f63 0S7Fibroblast growth factor receptor 1 / 0.655
4fkj 11KCyclin-dependent kinase 2 2.7.11.22 0.655
2r3l SCWCyclin-dependent kinase 2 2.7.11.22 0.654
3ezr EZRCyclin-dependent kinase 2 2.7.11.22 0.654
3nux 3NVCyclin-dependent kinase 6 2.7.11.22 0.654
2c5n CK8Cyclin-dependent kinase 2 2.7.11.22 0.652
4ek6 10KCyclin-dependent kinase 2 2.7.11.22 0.651
3ql8 X01Cyclin-dependent kinase 2 2.7.11.22 0.650
4fkr 45KCyclin-dependent kinase 2 2.7.11.22 0.650