sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ofe | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1ofe | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 1.109 | |
| 1lm1 | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.948 | |
| 1ofd | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.943 | |
| 2z6i | FMN | 2-nitropropane dioxygenase | / | 0.833 | |
| 1llz | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.828 | |
| 1llw | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.812 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.808 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.802 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.765 | |
| 5cpm | FNR | NADH:flavin oxidoreductase | / | 0.765 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.764 | |
| 2hsa | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.763 | |
| 1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.759 | |
| 2gqa | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.758 | |
| 3l5l | FMN | Xenobiotic reductase | / | 0.757 | |
| 3l67 | FMN | Xenobiotic reductase | / | 0.755 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.751 | |
| 4utm | FNR | Xenobiotic reductase | / | 0.747 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.744 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.743 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.737 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.736 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.734 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.734 | |
| 3hf3 | FMN | Chromate reductase | / | 0.732 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.730 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.728 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.727 | |
| 1z44 | FMN | NADPH dehydrogenase | / | 0.722 | |
| 4jic | FMN | GTN Reductase | / | 0.720 | |
| 4qnw | FMN | Chanoclavine-I aldehyde reductase easA | / | 0.719 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.718 | |
| 1jub | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.717 | |
| 1z48 | FMN | NADPH dehydrogenase | / | 0.717 | |
| 1qcw | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.716 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.714 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.713 | |
| 4z9r | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.712 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.711 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.710 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.704 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.701 | |
| 4e2b | FMN | Dehydrogenase | / | 0.699 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.698 | |
| 4utl | FNR | Xenobiotic reductase | / | 0.698 | |
| 1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.696 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.693 | |
| 4e2d | FMN | Dehydrogenase | / | 0.692 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.691 | |
| 4cw5 | FMN | DfnA | / | 0.690 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.687 | |
| 1ea0 | FMN | Glutamate synthase [NADPH] large chain | 1.4.1.13 | 0.686 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.686 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.685 | |
| 1gwj | FMN | Morphinone reductase | / | 0.684 | |
| 3bw3 | FMN | Putative 2-nitropropane dioxygenase | / | 0.684 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.683 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.679 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.677 | |
| 4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.677 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.675 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.675 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.674 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.673 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.672 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.671 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.671 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.668 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.665 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.664 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.664 | |
| 2h8x | FMN | XenA | / | 0.663 | |
| 4r38 | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.662 | |
| 2j6x | FMN | Lactate oxidase | / | 0.661 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.661 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.659 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.657 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.656 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.655 | |
| 4q4k | FMN | Uncharacterized protein | / | 0.653 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.650 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.650 |