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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1llq NAD NAD-dependent malic enzyme, mitochondrial 1.1.1.38

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1llq NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 1.011
1o0s NAINAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.780
1efl NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.736
1efk NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.719
1qr6 NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.719
1pj3 NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.710
1do8 NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.709
4ebf NADPhosphonate dehydrogenase 1.20.1.1 0.709
1gq2 NAPNADP-dependent malic enzyme 1.1.1.40 0.701
3cea NADMyo-inositol 2-dehydrogenase-like (Promiscuous) / 0.700
1gz4 ATPNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.690
2dvm NAD439aa long hypothetical malate oxidoreductase (NAD) [malic enzyme] / 0.679
2vq3 NAPMetalloreductase STEAP3 / 0.674
3p2o NADBifunctional protein FolD / 0.674
3anm NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.1.1.267 0.669
1yl7 NAI4-hydroxy-tetrahydrodipicolinate reductase / 0.668
3x2f NAIAdenosylhomocysteinase / 0.662
3ing NDPHomoserine dehydrogenase related protein / 0.660
1guy NADMalate dehydrogenase / 0.659
1pj2 NAINAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.658
3b20 NADGlyceraldehyde-3-phosphate dehydrogenase / 0.655
3nt2 NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.655
1pj4 ATPNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.654