Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1c5n ESI Prothrombin 3.4.21.5

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1c5n ESIProthrombin 3.4.21.5 0.834
3hat GLY_VAL_ARG_RNGProthrombin 3.4.21.5 0.748
2v3h I25Prothrombin 3.4.21.5 0.743
1gj4 132Prothrombin 3.4.21.5 0.742
1ypl RA8Prothrombin 3.4.21.5 0.741
3biv 11UProthrombin 3.4.21.5 0.741
2zhf 49UProthrombin 3.4.21.5 0.740
1riw OSCProthrombin 3.4.21.5 0.739
2gde SN3Prothrombin 3.4.21.5 0.738
2zi2 24UProthrombin 3.4.21.5 0.737
2zfq 45UProthrombin 3.4.21.5 0.734
2ziq 26UProthrombin 3.4.21.5 0.733
2bdy UNBProthrombin 3.4.21.5 0.732
2zg0 50UProthrombin 3.4.21.5 0.731
4ayy 9MXProthrombin 3.4.21.5 0.731
2zhq 27UProthrombin 3.4.21.5 0.730
2znk 31UProthrombin 3.4.21.5 0.730
4baq M4ZProthrombin 3.4.21.5 0.730
4bah MELProthrombin 3.4.21.5 0.729
4bam MM9Prothrombin 3.4.21.5 0.729
1k22 MELProthrombin 3.4.21.5 0.728
4bak M67Prothrombin 3.4.21.5 0.728
4bao MVFProthrombin 3.4.21.5 0.728
1ypk CCRProthrombin 3.4.21.5 0.727
2zfr 46UProthrombin 3.4.21.5 0.727
1d4p BPPProthrombin 3.4.21.5 0.726
4ban M6SProthrombin 3.4.21.5 0.725
1ypm RA4Prothrombin 3.4.21.5 0.724
4e7r 0NWProthrombin 3.4.21.5 0.724
3utu 1TSProthrombin 3.4.21.5 0.723
4az2 9MUProthrombin 3.4.21.5 0.723
2zhw 12UProthrombin 3.4.21.5 0.722
1zsk 421Coagulation factor XI 3.4.21.27 0.721
2zgx 29UProthrombin 3.4.21.5 0.720
1o2g 696Prothrombin 3.4.21.5 0.716
2zda 32UProthrombin 3.4.21.5 0.715
4ax9 N5NProthrombin 3.4.21.5 0.714
2v3o I26Prothrombin 3.4.21.5 0.712
2zhe 13UProthrombin 3.4.21.5 0.712
1lpk CBBCoagulation factor X 3.4.21.6 0.711
1gj5 130Prothrombin 3.4.21.5 0.705
1c1w BAHProthrombin 3.4.21.5 0.704
4ayv 9MQProthrombin 3.4.21.5 0.703
1vja 7INUrokinase-type plasminogen activator 3.4.21.73 0.699
1wqv PSMCoagulation factor VII 3.4.21.21 0.698
2bok 784Coagulation factor X 3.4.21.6 0.696
1wtg 3BPCoagulation factor VII 3.4.21.21 0.694
1k21 IGNProthrombin 3.4.21.5 0.691
1o0d 163Prothrombin 3.4.21.5 0.688
3biu 10UProthrombin 3.4.21.5 0.686
2pks G44Prothrombin 3.4.21.5 0.679
1c1u BAIProthrombin 3.4.21.5 0.676
2cf9 348Prothrombin 3.4.21.5 0.675
1owi 426Urokinase-type plasminogen activator 3.4.21.73 0.672
4jpc 1M6Beta-secretase 1 3.4.23.46 0.669
2zp0 PI0Coagulation factor VII 3.4.21.21 0.668
3l5d BDVBeta-secretase 1 3.4.23.46 0.665
4djw 0KPBeta-secretase 1 3.4.23.46 0.665
4djy 0KRBeta-secretase 1 3.4.23.46 0.663
4acu QN7Beta-secretase 1 3.4.23.46 0.662
4djv 0KMBeta-secretase 1 3.4.23.46 0.662
4joo 1M4Beta-secretase 1 3.4.23.46 0.662
1drt PCVClavaminate synthase 1 1.14.11.21 0.660
2cf8 ESHProthrombin 3.4.21.5 0.660
3l5e BDWBeta-secretase 1 3.4.23.46 0.657
1r35 I58Nitric oxide synthase, inducible 1.14.13.39 0.656
2c4f GILCoagulation factor VII 3.4.21.21 0.652
1pw6 FRBInterleukin-2 / 0.650