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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1bdu DUR Thymidylate synthase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1bdu DURThymidylate synthase / 0.828
1bid UMPThymidylate synthase / 0.761
1ddu DDUThymidylate synthase / 0.739
1bp6 UMPThymidylate synthase / 0.718
1tsy UMPThymidylate synthase / 0.715
1aob DDUThymidylate synthase / 0.712
4h0u UMPThymidylate synthase / 0.712
1vzb UMPThymidylate synthase / 0.711
4eb4 UMPThymidylate synthase 2.1.1.45 0.707
1tsx UMPThymidylate synthase / 0.703
1bp0 UMPThymidylate synthase / 0.700
1bpj UMPThymidylate synthase / 0.699
3dga UMPBifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.690
4e5o UMPThymidylate synthase 2.1.1.45 0.687
1njd UMPThymidylate synthase / 0.683
2tdm UMPThymidylate synthase / 0.680
1vza UMPThymidylate synthase / 0.678
2fto TMPThymidylate synthase / 0.677
2vet UMPThymidylate synthase / 0.674
1jmh UMPThymidylate synthase / 0.672
1tsv UMPThymidylate synthase / 0.671
1nja DCMThymidylate synthase / 0.668
1tdu DURThymidylate synthase / 0.666
3bgx TMPThymidylate synthase / 0.664
5by6 UMPThymidylate synthase / 0.659
3dg8 UMPBifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.655
1tys TMPThymidylate synthase / 0.652