Structural Chemogenomics Group
Therapeutic Innovation Laboratory UMR7200
Formerly: Bioinformatics of the Drug
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Breaking News
Cazorla et al. (2011) J Clin Invest, 121, 1846-1857
Identification of the first TrkB antagonist with anxiolytic and antidepressant properties
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New Features
sc-PDB 2011
New Features:
Costumise your query using the Cavity Volume.
The release contains 9877 entries
3034 different proteins
5339 different ligands
News & Events
Past Events
20-24/June/2010
2nd Strasbourg Summer School on Chemoinformatics. More »
Contact
Phone, fax, e-mail
Address: 74,Route du Rhin - BP.60024
Illkirch - France
Telephone: +33 3 90 24 42 35
FAX: +33 3 90 24 43 10
Secretary: +33 3 90 24 42 20
E-mail: rognan@unistra.fr
Welcome to Our Website
Our Mission
Medicinal Chemistry has just entered a new era with the complete sequencing of a human genome. The number of potentially interesting drug targets will no doubt dramatically increase in the incoming years. To just give an idea of the revolution to come, about 500 targets are currently used by the modern pharmacopoeia, but between 5,000 and 10,000 are foreseen in a near future. A significant number of these new targets will probably be orphan targets for which no or very few information on endogenous ligands will be available. To get first insights into the molecular structures of such ligands, virtual screening of chemical databases against a protein active site or a pharmacophore is an emerging technique that allow to enrich a reduced dataset in true hits.
Databases
sc-PDB
Ann annotated database of druggable binding sites from the protein databank
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BioinfoDB
A database of commercialy available drug-like compounds
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