sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Tyrosine--tRNA ligase, cytoplasmic
ID:	SYYC_HUMAN
AC:	P54577
Organism:	Homo sapiens
Reign:	Eukaryota
TaxID:	9606
EC Number:	6.1.1.1

---

Chains:

Chain Name:	Percentage of Residues within binding site
A	100 %

---

Ligand binding site composition:

B-Factor:	33.263
Number of residues:	26
Including
Standard Amino Acids:	24
Non Standard Amino Acids:	0
Water Molecules:	2
Cofactors:
Metals:

---

Cavity properties

Ligandability	Volume (Å3)
0.278	324.000

% Hydrophobic	% Polar
45.83	54.17
According to VolSite

HET Code:	STL
Formula:	C14H12O3
Molecular weight:	228.243 g/mol
DrugBank ID:	DB02709
Buried Surface Area:	61.74 %
Polar Surface area:	60.69 Å2

Number of
H-Bond Acceptors:	3
H-Bond Donors:	3
Rings:	2
Aromatic rings:	2
Anionic atoms:	0
Cationic atoms:	0
Rule of Five Violation:	0
Rotatable Bonds:	2

---

Mass center Coordinates

X	Y	Z
-9.18382	12.0534	-9.78182

• 2D View
• 3D View