sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Baculoviral IAP repeat-containing protein 8
ID:	BIRC8_HUMAN
AC:	Q96P09
Organism:	Homo sapiens
Reign:	Eukaryota
TaxID:	9606
EC Number:	/

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Chains:

Chain Name:	Percentage of Residues within binding site
E	20 %
F	80 %

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Ligand binding site composition:

B-Factor:	25.181
Number of residues:	22
Including
Standard Amino Acids:	22
Non Standard Amino Acids:	0
Water Molecules:	0
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
0.562	327.375

% Hydrophobic	% Polar
43.30	56.70
According to VolSite

HET Code:	ALA_VAL_PRO_ILE
Formula:	C19H35N4O4
Molecular weight:	383.506 g/mol
DrugBank ID:	-
Buried Surface Area:	46.64 %
Polar Surface area:	123.21 Å2

Number of
H-Bond Acceptors:	4
H-Bond Donors:	3
Rings:	1
Aromatic rings:	0
Anionic atoms:	0
Cationic atoms:	1
Rule of Five Violation:	0
Rotatable Bonds:	9

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Mass center Coordinates

X	Y	Z
117.632	95.2979	26.201

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