sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Annexin A5
ID:	ANXA5_HUMAN
AC:	P08758
Organism:	Homo sapiens
Reign:	Eukaryota
TaxID:	9606
EC Number:	/

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Chains:

Chain Name:	Percentage of Residues within binding site
A	93 %
B	7 %

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Ligand binding site composition:

B-Factor:	8.437
Number of residues:	28
Including
Standard Amino Acids:	28
Non Standard Amino Acids:	0
Water Molecules:	0
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
0.475	604.125

% Hydrophobic	% Polar
41.90	58.10
According to VolSite

HET Code:	K21
Formula:	C25H33N2O2S
Molecular weight:	425.607 g/mol
DrugBank ID:	DB02929
Buried Surface Area:	35.11 %
Polar Surface area:	59.28 Å2

Number of
H-Bond Acceptors:	3
H-Bond Donors:	1
Rings:	4
Aromatic rings:	2
Anionic atoms:	0
Cationic atoms:	1
Rule of Five Violation:	0
Rotatable Bonds:	6

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Mass center Coordinates

X	Y	Z
22.9839	16.9583	-11.949

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