|A   R23|A  Y146|A  A194|A  L195|A  P196|A  C198|A  H199|A  Q217|A  R218|A  S219|A  A220|A  D221|A  I222|A  L224|A  G225|A  V226|A  F228|A  N229|A  H259|A  W261|A  A315
000101000000000000000000100000000000000010000000000000000000000000010100000100000000000010000000000000000000000000000000000000000000000000011000000100000000000000000000