sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
9mht	SAH	Modification methylase HhaI	2.1.1.37

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
9mht	SAH	Modification methylase HhaI	2.1.1.37	1.000
7mht	SAH	Modification methylase HhaI	2.1.1.37	0.625
1skm	SAH	Modification methylase HhaI	2.1.1.37	0.608
2i9k	SAH	Modification methylase HhaI	2.1.1.37	0.588
2zcj	SAH	Modification methylase HhaI	2.1.1.37	0.580
5mht	SAH	Modification methylase HhaI	2.1.1.37	0.579
10mh	SAH	Modification methylase HhaI	2.1.1.37	0.576
2z6u	SAH	Modification methylase HhaI	2.1.1.37	0.568
1mht	SAH	Modification methylase HhaI	2.1.1.37	0.567
1fjx	SAH	Modification methylase HhaI	2.1.1.37	0.563
4mht	SAH	Modification methylase HhaI	2.1.1.37	0.560
2hmy	SAM	Modification methylase HhaI	2.1.1.37	0.503