sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
8mht	SAH	Modification methylase HhaI	2.1.1.37

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
8mht	SAH	Modification methylase HhaI	2.1.1.37	1.000
5mht	SAH	Modification methylase HhaI	2.1.1.37	0.810
2uyh	SAH	Modification methylase HhaI	2.1.1.37	0.662
7mht	SAH	Modification methylase HhaI	2.1.1.37	0.635
3mht	SAH	Modification methylase HhaI	2.1.1.37	0.621
2c7q	SAH	Modification methylase HhaI	2.1.1.37	0.591
1mht	SAH	Modification methylase HhaI	2.1.1.37	0.577
2zcj	SAH	Modification methylase HhaI	2.1.1.37	0.570
9mht	SAH	Modification methylase HhaI	2.1.1.37	0.489
2z6u	SAH	Modification methylase HhaI	2.1.1.37	0.486
3qv2	SAH	5-cytosine DNA methyltransferase	/	0.445
4da4	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.442