Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 1.000 | |
4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.673 | |
1dre | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.643 | |
4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.616 | |
1rx2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.610 | |
4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.608 | |
3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.607 | |
1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.606 | |
2zza | FOL | Dihydrofolate reductase | / | 0.600 | |
3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.598 | |
3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.597 | |
4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.597 | |
3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.593 | |
3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.591 | |
3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.591 | |
1qzf | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.589 | |
1rh3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.586 | |
2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.586 | |
4m7v | RAR | Dihydrofolate reductase | / | 0.583 | |
3qly | 55V | Uncharacterized protein | / | 0.580 | |
3tq9 | MTX | Dihydrofolate reductase | / | 0.580 | |
4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.579 | |
1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.578 | |
1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.578 | |
3qlx | QLR | Uncharacterized protein | / | 0.578 | |
2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.577 | |
3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.575 | |
3fre | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.574 | |
3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.572 | |
3tqb | FOL | Dihydrofolate reductase | / | 0.569 | |
3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.569 | |
4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.569 | |
1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 0.568 | |
3cse | N22 | Uncharacterized protein | / | 0.567 | |
4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.567 | |
4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.566 | |
3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.564 | |
1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.562 | |
3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.562 | |
3tq8 | TOP | Dihydrofolate reductase | / | 0.562 | |
3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.561 | |
1dyr | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.560 | |
4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.559 | |
3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.557 | |
1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.556 | |
3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.556 | |
3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.554 | |
3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.553 | |
3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.552 | |
3eek | 53S | Uncharacterized protein | / | 0.551 | |
1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.550 | |
3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.550 | |
4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.549 | |
3fyv | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.548 | |
4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.548 | |
3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.546 | |
3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.544 | |
3sqy | Q11 | Dihydrofolate reductase | 1.5.1.3 | 0.544 | |
1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.542 | |
4h98 | 14Q | Uncharacterized protein | / | 0.542 | |
1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.541 | |
3eem | 53V | Uncharacterized protein | / | 0.541 | |
3sa1 | 6DR | Dihydrofolate reductase | / | 0.541 | |
3sr5 | Q12 | Dihydrofolate reductase | 1.5.1.3 | 0.540 | |
4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.540 | |
3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.539 | |
1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.537 | |
2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.537 | |
2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.537 | |
3sai | 9DR | Dihydrofolate reductase | / | 0.537 | |
3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.536 | |
3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.534 | |
3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.533 | |
4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.531 | |
4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.530 | |
4p66 | MTX | Dihydrofolate reductase | / | 0.530 | |
2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.529 | |
1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.528 | |
4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.528 | |
3eel | 53T | Uncharacterized protein | / | 0.527 | |
1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.526 | |
3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.526 | |
2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.524 | |
3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.524 | |
3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.523 | |
3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.523 | |
4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.523 | |
4p68 | MTX | Dihydrofolate reductase | / | 0.522 | |
1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.521 | |
3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.520 | |
3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.519 | |
1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.518 | |
2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.518 | |
1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.517 | |
1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.516 | |
3rg9 | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.514 | |
3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.513 | |
3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.509 | |
4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.509 | |
5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.507 | |
1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
3m09 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.504 | |
2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.503 | |
3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.503 | |
3jwm | 5WB | Dihydrofolate reductase | / | 0.503 | |
4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.503 | |
3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.502 | |
4ele | 31I | Dihydrofolate reductase | / | 0.502 | |
2c3o | TPP | Pyruvate synthase | / | 0.501 | |
3eej | 53R | Uncharacterized protein | / | 0.501 | |
3zhb | NAP | Putative dehydrogenase | / | 0.501 | |
3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.500 | |
3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.500 | |
1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.499 | |
2w3w | VG9 | Dihydrofolate reductase | / | 0.499 | |
3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.498 | |
4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
1og5 | SWF | Cytochrome P450 2C9 | / | 0.496 | |
3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.496 | |
3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
1db1 | VDX | Vitamin D3 receptor | / | 0.492 | |
1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.492 | |
2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.492 | |
4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.492 | |
1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.490 | |
4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.490 | |
4zas | TYD | CalS13 | / | 0.490 | |
1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.489 | |
2ayr | L4G | Estrogen receptor | / | 0.489 | |
3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.489 | |
4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.489 | |
4qi9 | MTX | Dihydrofolate reductase | / | 0.489 | |
1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.488 | |
2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.488 | |
3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
3sa2 | 7DR | Dihydrofolate reductase | / | 0.488 | |
4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.488 | |
4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.488 | |
4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.488 | |
1zdw | FLV | Prenyltransferase | / | 0.487 | |
3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.487 | |
3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.487 | |
4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.487 | |
1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.486 | |
3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.486 | |
1ie9 | VDX | Vitamin D3 receptor | / | 0.485 | |
1td2 | PXL | Pyridoxal kinase PdxY | / | 0.485 | |
2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.485 | |
2wue | KEK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.485 | |
4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.485 | |
4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.485 | |
1qkn | RAL | Estrogen receptor beta | / | 0.484 | |
1rp4 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.484 | |
4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.484 | |
2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.483 | |
2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.483 | |
2hcd | BIV | Vitamin D3 receptor A | / | 0.483 | |
2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.483 | |
2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.483 | |
3a0i | AJI | Glucokinase | 2.7.1.2 | 0.483 | |
3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.483 | |
3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.483 | |
3reo | EUG | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.483 | |
3up3 | XCA | aceDAF-12 | / | 0.483 | |
3w0h | W12 | Vitamin D3 receptor | / | 0.483 | |
1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.482 | |
2yej | XQK | Heat shock protein HSP 90-alpha | / | 0.482 | |
3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.482 | |
1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
5d7q | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.481 | |
1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.480 | |
3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.480 | |
3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.480 | |
4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.480 | |
5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.480 | |
2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.479 | |
3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.479 | |
4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.479 | |
4iw8 | KN3 | Estrogen receptor | / | 0.479 | |
1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
2hb8 | MVD | Vitamin D3 receptor | / | 0.478 | |
3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
3m31 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.478 | |
3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.478 | |
4mlh | VO2 | Glucokinase | 2.7.1.2 | 0.478 | |
4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.477 | |
3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.477 | |
3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.477 | |
4isg | 1FY | Glucokinase | 2.7.1.2 | 0.477 | |
5ecc | NAP | Dehydrofolate reductase type I | / | 0.477 | |
1jtq | LY3 | Thymidylate synthase | / | 0.476 | |
2acw | UPG | Glycosyltransferase | / | 0.476 | |
2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.476 | |
4g20 | 484 | Vitamin D3 receptor A | / | 0.476 | |
4o95 | 245 | Cytokinin dehydrogenase 4 | / | 0.476 | |
3pwh | ZMA | Adenosine receptor A2a | / | 0.476 | |
1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.475 | |
1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.475 | |
1zw9 | H64 | ATP-dependent molecular chaperone HSP82 | / | 0.475 | |
2fsz | OHT | Estrogen receptor beta | / | 0.475 | |
3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.475 | |
3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.475 | |
5a28 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.475 | |
5d7p | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.475 | |
1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
2has | C3O | Vitamin D3 receptor | / | 0.474 | |
2qk8 | MTX | Dihydrofolate reductase | / | 0.474 | |
2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.474 | |
2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.474 | |
3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.474 | |
3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
3tda | PN0 | Cytochrome P450 2D6 | / | 0.474 | |
3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.474 | |
4elb | 34S | Dihydrofolate reductase | / | 0.474 | |
4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.474 | |
4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
1r2j | FAD | FkbI | / | 0.473 | |
1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.473 | |
1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.473 | |
2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.473 | |
2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.473 | |
4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.472 | |
1lud | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.472 | |
2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
3fl8 | RAR | Dihydrofolate reductase | / | 0.472 | |
3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
1xp9 | AIJ | Estrogen receptor | / | 0.471 | |
2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.471 | |
3ngl | NAP | Bifunctional protein FolD | / | 0.471 | |
3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.471 | |
4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
5jtb | ZMA | Adenosine receptor A2a | / | 0.471 | |
1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.470 | |
2oax | SNL | Mineralocorticoid receptor | / | 0.470 | |
2pda | TPP | Pyruvate synthase | / | 0.470 | |
2ywv | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | / | 0.470 | |
3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.470 | |
3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.470 | |
3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
4l8u | 9AZ | Serum albumin | / | 0.470 | |
1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
1rx4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
1u3r | 338 | Estrogen receptor beta | / | 0.469 | |
2hb7 | O1C | Vitamin D3 receptor | / | 0.469 | |
2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.469 | |
2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.469 | |
2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
4g1z | 0VP | Vitamin D3 receptor A | / | 0.469 | |
4ia1 | BIV | Vitamin D3 receptor A | / | 0.469 | |
4zqc | F6F | Tryptophan synthase alpha chain | / | 0.469 | |
5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.469 | |
1s19 | MC9 | Vitamin D3 receptor | / | 0.468 | |
2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.468 | |
3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.468 | |
3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.468 | |
3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.468 | |
3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
3vrv | YSD | Vitamin D3 receptor | / | 0.468 | |
4dhy | S41 | Glucokinase | 2.7.1.2 | 0.468 | |
4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.467 | |
1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.467 | |
2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.467 | |
2o4j | VD4 | Vitamin D3 receptor | / | 0.467 | |
2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.467 | |
2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.467 | |
2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.467 | |
2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.467 | |
3vrw | YS5 | Vitamin D3 receptor | / | 0.467 | |
1g28 | FMN | PHY3 | / | 0.466 | |
1upw | 444 | Oxysterols receptor LXR-beta | / | 0.466 | |
2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.466 | |
3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
3drr | R8E | Gag-Pol polyprotein | 2.7.7.49 | 0.466 | |
3kpz | ZNE | Vitamin D3 receptor | / | 0.466 | |
3m7r | VDX | Vitamin D3 receptor | / | 0.466 | |
4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
1bq1 | CB3 | Thymidylate synthase | / | 0.465 | |
1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.465 | |
3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.465 | |
3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.465 | |
4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
4iah | 1DX | Alr2278 protein | / | 0.465 | |
4iui | 1GQ | Estrogen receptor | / | 0.465 | |
4iv2 | 1GR | Estrogen receptor | / | 0.465 | |
4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.465 | |
4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.465 | |
5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.465 | |
1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.464 | |
1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.464 | |
2egs | SAH | Diphthine synthase | / | 0.464 | |
2p2x | SAH | Diphthine synthase | / | 0.464 | |
2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
2wpx | ACO | Orf14 | / | 0.464 | |
3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.464 | |
3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
3pi0 | F91 | Endothiapepsin | 3.4.23.22 | 0.464 | |
3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
4nmb | FAD | Bifunctional protein PutA | / | 0.464 | |
5dp2 | NAP | CurF | / | 0.464 | |
1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.463 | |
3imx | B84 | Glucokinase | 2.7.1.2 | 0.463 | |
3up0 | D7S | aceDAF-12 | / | 0.463 | |
3w0y | DS4 | Vitamin D3 receptor | / | 0.463 | |
1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
1fkw | PUR | Adenosine deaminase | 3.5.4.4 | 0.462 | |
1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
1kek | HTL | Pyruvate synthase | / | 0.462 | |
1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.462 | |
2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.462 | |
2ham | C33 | Vitamin D3 receptor | / | 0.462 | |
2jfa | RAL | Estrogen receptor | / | 0.462 | |
2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.462 | |
3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.462 | |
3nrc | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.462 | |
4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.462 | |
4ce3 | L4V | ATP-dependent molecular chaperone HSP82 | / | 0.462 | |
4eso | NAP | Putative oxidoreductase | / | 0.462 | |
4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.462 | |
4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.462 | |
4rup | H97 | Vitamin D3 receptor A | / | 0.462 | |
5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.462 | |
1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.461 | |
1olm | VTQ | SEC14-like protein 2 | / | 0.461 | |
1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.461 | |
1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.461 | |
1uxj | NAD | Malate dehydrogenase | / | 0.461 | |
2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.461 | |
3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.461 | |
3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.461 | |
3vt6 | 5YI | Vitamin D3 receptor | / | 0.461 | |
4bqr | IBH | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.461 | |
4elg | 52J | Dihydrofolate reductase | / | 0.461 | |
4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.461 | |
4ruo | BIV | Vitamin D3 receptor A | / | 0.461 | |
1bsv | NDP | GDP-L-fucose synthase | / | 0.460 | |
1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
1f4f | TP3 | Thymidylate synthase | / | 0.460 | |
1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.460 | |
2cjp | VPR | Epoxide hydrolase | / | 0.460 | |
2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
3dol | GWI | Pol protein | / | 0.460 | |
3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.460 | |
3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.460 | |
3o9l | LPN | Renin | 3.4.23.15 | 0.460 | |
4ap7 | F47 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.460 | |
4j6d | TES | Cytochrome P450 monooxygenase | / | 0.460 | |
4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.460 | |
4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.460 | |
4y6g | F6F | Tryptophan synthase alpha chain | / | 0.460 | |
5k2b | ZMA | Adenosine receptor A2a | / | 0.460 | |
1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.459 | |
1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.459 | |
2bxq | IMN | Serum albumin | / | 0.459 | |
2i1v | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.459 | |
2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
2wuu | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
2ync | YNC | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
3bus | SAH | Demethylrebeccamycin-D-glucose O-methyltransferase | / | 0.459 | |
3l6j | Z90 | Alr2278 protein | / | 0.459 | |
3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.459 | |
3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.459 | |
3s79 | ASD | Aromatase | 1.14.14.14 | 0.459 | |
4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.459 | |
4itf | TFY | Vitamin D3 receptor | / | 0.459 | |
4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.459 | |
4jqh | 1MF | Alr2278 protein | / | 0.459 | |
4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.459 | |
5k2a | ZMA | Adenosine receptor A2a | / | 0.459 | |
1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.458 | |
1wpg | ADP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.458 | |
2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.458 | |
2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.458 | |
2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.458 | |
2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.458 | |
3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
3i53 | SAH | 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | / | 0.458 | |
3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
4ax8 | ADP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.458 | |
4elf | 35I | Dihydrofolate reductase | / | 0.458 | |
4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.458 | |
4g1y | 0VO | Vitamin D3 receptor A | / | 0.458 | |
4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.458 | |
1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.457 | |
1kzj | CB3 | Thymidylate synthase | / | 0.457 | |
1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
1rg7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
1rkg | VD1 | Vitamin D3 receptor | / | 0.457 | |
1tl7 | FOK | Adenylate cyclase type 2 | / | 0.457 | |
1tl7 | FOK | Adenylate cyclase type 5 | / | 0.457 | |
2bj4 | OHT | Estrogen receptor | / | 0.457 | |
2c42 | TPP | Pyruvate synthase | / | 0.457 | |
2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
2uza | HTL | Pyruvate synthase | / | 0.457 | |
2wpw | ACO | Orf14 | / | 0.457 | |
3gl2 | D3M | DdmC | / | 0.457 | |
3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.457 | |
3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.457 | |
3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.457 | |
4ap1 | NAP | Steroid monooxygenase | / | 0.457 | |
4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.457 | |
4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.457 | |
4dli | IRG | Mitogen-activated protein kinase 14 | / | 0.457 | |
4g8b | HL6 | Alpha/beta hydrolase fold protein | / | 0.457 | |
4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.457 | |
4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.457 | |
4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
4lvb | 20N | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.457 | |
4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.457 | |
1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.456 | |
1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.456 | |
1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.456 | |
1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.456 | |
2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.456 | |
2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.456 | |
2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.456 | |
3b6z | CO7 | Enoyl reductase LovC | 1 | 0.456 | |
3f8k | COA | Uncharacterized protein | / | 0.456 | |
3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.456 | |
3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.456 | |
3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
3p9t | TCL | Repressor | / | 0.456 | |
3t37 | FAD | Pyridoxine 4-oxidase | / | 0.456 | |
3vi7 | CBD | Hematopoietic prostaglandin D synthase | / | 0.456 | |
3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.456 | |
3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.456 | |
4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.456 | |
4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.456 | |
4l17 | DNQ | Glutamate receptor 2 | / | 0.456 | |
4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.456 | |
4rrj | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.456 | |
1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.455 | |
1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.455 | |
1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.455 | |
2x20 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.455 | |
3elu | SAM | Methyltransferase | / | 0.455 | |
3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.455 | |
3lm4 | HPX | Catechol 2,3-dioxygenase | / | 0.455 | |
3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.455 | |
3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.455 | |
4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.455 | |
4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.455 | |
4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.455 | |
5uvi | ZMA | Adenosine receptor A2a | / | 0.455 | |
3eml | ZMA | Adenosine receptor A2a | / | 0.455 | |
1cjk | FOK | Adenylate cyclase type 2 | / | 0.454 | |
1cjk | FOK | Adenylate cyclase type 5 | / | 0.454 | |
1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
1dtn | APG | Mandelate racemase | / | 0.454 | |
1kce | CB3 | Thymidylate synthase | / | 0.454 | |
2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.454 | |
2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.454 | |
2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.454 | |
2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.454 | |
2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.454 | |
3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.454 | |
3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.454 | |
3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.454 | |
3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.454 | |
3sso | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.454 | |
3wnz | ADP | Alanine--anticapsin ligase | / | 0.454 | |
4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.454 | |
4c68 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.454 | |
4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
4ie0 | PD2 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.454 | |
4j6c | STR | Cytochrome P450 monooxygenase | / | 0.454 | |
4o71 | CPB | Bromodomain-containing protein 4 | / | 0.454 | |
5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.454 | |
1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
1fmj | RTL | Retinol dehydratase | / | 0.453 | |
1k6m | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 | 2.7.1.105 | 0.453 | |
1mlz | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.453 | |
1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
1zky | 689 | Estrogen receptor | / | 0.453 | |
2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
2oal | FAD | Flavin-dependent tryptophan halogenase RebH | 1.14.19.9 | 0.453 | |
2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.453 | |
2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.453 | |
2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
2z6i | FMN | 2-nitropropane dioxygenase | / | 0.453 | |
3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.453 | |
3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.453 | |
4bmp | FMN | Protein NrdI | / | 0.453 | |
4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
4ia2 | BIV | Vitamin D3 receptor A | / | 0.453 | |
4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.453 | |
4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
5fkm | TDC | Tetracycline repressor protein class D | / | 0.453 | |
3uza | T4G | Adenosine receptor A2a | / | 0.453 | |
1s0z | EB1 | Vitamin D3 receptor | / | 0.452 | |
1xdd | AAY | Integrin alpha-L | / | 0.452 | |
2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.452 | |
2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.452 | |
2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.452 | |
3anl | SYC | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.452 | |
3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.452 | |
3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
3vt9 | YI4 | Vitamin D3 receptor | / | 0.452 | |
3zv5 | BPY | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.452 | |
4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.452 | |
4ivw | 1GJ | Estrogen receptor | / | 0.452 | |
4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.452 | |
4lsl | 1YQ | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
4mfb | 29T | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.452 | |
1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.451 | |
1qlt | FAD | Vanillyl-alcohol oxidase | 1.1.3.38 | 0.451 | |
1rkh | VD2 | Vitamin D3 receptor | / | 0.451 | |
1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
1tw2 | ERT | Carminomycin 4-O-methyltransferase DnrK | 2.1.1.292 | 0.451 | |
1xpc | AIT | Estrogen receptor | / | 0.451 | |
2gj3 | FAD | Nitrogen fixation regulatory protein | 2.7.13.3 | 0.451 | |
2izk | GLL | Streptavidin | / | 0.451 | |
2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.451 | |
2r2g | EMF | Eugenol synthase 1 | 1.1.1.318 | 0.451 | |
3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
3nef | PYV | Abscisic acid receptor PYL1 | / | 0.451 | |
3njo | PYV | Abscisic acid receptor PYR1 | / | 0.451 | |
3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.451 | |
3rl3 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.451 | |
3t2w | BTN | Avidin/streptavidin | / | 0.451 | |
3uf6 | COD | Lmo1369 protein | / | 0.451 | |
3vtc | TK3 | Vitamin D3 receptor | / | 0.451 | |
3wtk | TH4 | Acetylcholine-binding protein | / | 0.451 | |
4a99 | MIY | TetX family tetracycline inactivation enzyme | / | 0.451 | |
4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.451 | |
4fhi | 0S4 | Vitamin D3 receptor A | / | 0.451 | |
4gm4 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.451 | |
4k5o | 1OT | M1 family aminopeptidase | 3.4.11 | 0.451 | |
4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.451 | |
4rw4 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.451 | |
4tyj | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.451 | |
6cox | S58 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.451 | |
1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.450 | |
1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.450 | |
1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
1zaf | 789 | Estrogen receptor beta | / | 0.450 | |
2apg | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.450 | |
2yg3 | FAD | Putrescine oxidase | / | 0.450 | |
2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.450 | |
2z3u | CRR | Cytochrome P450 | / | 0.450 | |
2zlc | VDX | Vitamin D3 receptor | / | 0.450 | |
3dle | GFA | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.450 | |
3k2h | LYA | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
3otq | MZL | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.450 | |
3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.450 | |
3w0a | DS5 | Vitamin D3 receptor | / | 0.450 | |
3w5t | LHP | Vitamin D3 receptor | / | 0.450 | |
3x06 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.450 | |
3x0a | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.450 | |
4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.450 | |
4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.450 | |
4fj0 | HHF | 17beta-hydroxysteroid dehydrogenase | / | 0.450 | |
4fqs | LYA | Thymidylate synthase ThyA | / | 0.450 | |
4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.450 | |
4gnc | ASO | Regucalcin | 3.1.1.17 | 0.450 | |
4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.450 | |
4ia3 | BIV | Vitamin D3 receptor A | / | 0.450 | |
4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.450 | |
4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 0.450 | |
4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
5k2c | ZMA | Adenosine receptor A2a | / | 0.450 | |
1ie8 | KH1 | Vitamin D3 receptor | / | 0.449 | |
1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.449 | |
1svl | ADP | Large T antigen | 3.6.4 | 0.449 | |
1txi | TX5 | Vitamin D3 receptor | / | 0.449 | |
1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.449 | |
1ykd | CMP | Adenylate cyclase | / | 0.449 | |
2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
2hc4 | VDX | Vitamin D3 receptor A | / | 0.449 | |
2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.449 | |
2zhf | 49U | Prothrombin | 3.4.21.5 | 0.449 | |
3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.449 | |
3glu | LYS_VAL_MET | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.449 | |
3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.449 | |
3kk6 | CEL | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.449 | |
3ry2 | BTN | Streptavidin | / | 0.449 | |
3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.449 | |
3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.449 | |
3w0c | 6DS | Vitamin D3 receptor | / | 0.449 | |
3w0i | O11 | Vitamin D3 receptor | / | 0.449 | |
4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
4c73 | TLH | 3-oxoacyl-ACP synthase | / | 0.449 | |
4cuk | NAI | D-lactate dehydrogenase | / | 0.449 | |
4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.449 | |
4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.449 | |
4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.449 | |
4rrm | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.449 | |
3rey | XAC | Adenosine receptor A2a | / | 0.449 | |
1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.448 | |
1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.448 | |
1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
2ewn | BTX | Bifunctional ligase/repressor BirA | / | 0.448 | |
2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.448 | |
2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.448 | |
2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.448 | |
2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.448 | |
2pca | SAH | Diphthine synthase | / | 0.448 | |
2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.448 | |
2x9d | ITC | Tetracycline repressor protein class D | / | 0.448 | |
2zyn | BCD | Periplasmic binding protein | / | 0.448 | |
3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.448 | |
3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.448 | |
3c1o | NAP | Eugenol synthase | / | 0.448 | |
3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.448 | |
3cgb | COA | Coenzyme A disulfide reductase | / | 0.448 | |
3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.448 | |
3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.448 | |
3saz | 043 | Malate synthase G | / | 0.448 | |
3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.448 | |
4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.448 | |
4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.448 | |
4dch | 4DC | Glucokinase | 2.7.1.2 | 0.448 | |
4eiy | ZMA | Adenosine receptor A2a | / | 0.448 | |
4ktt | SAM | S-adenosylmethionine synthase isoform type-2 | 2.5.1.6 | 0.448 | |
4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.448 | |
1aj2 | 2PH | Dihydropteroate synthase | / | 0.447 | |
1d4p | BPP | Prothrombin | 3.4.21.5 | 0.447 | |
1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.447 | |
1dna | CB3 | Thymidylate synthase | / | 0.447 | |
1srh | MOB | Streptavidin | / | 0.447 | |
1syn | F89 | Thymidylate synthase | / | 0.447 | |
1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.447 | |
2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.447 | |
2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.447 | |
2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.447 | |
2nni | MTK | Cytochrome P450 2C8 | / | 0.447 | |
2pun | ACP | Methylthioribose kinase | 2.7.1.100 | 0.447 | |
3a8w | ATP | Protein kinase C iota type | 2.7.11.13 | 0.447 | |
3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.447 | |
3b03 | VNR | Isopentenyl-diphosphate delta-isomerase | / | 0.447 | |
3gwf | NAP | Cyclohexanone monooxygenase | / | 0.447 | |
3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.447 | |
3pll | F06 | Endothiapepsin | 3.4.23.22 | 0.447 | |
3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.447 | |
3qts | X46 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
3vt4 | 5YI | Vitamin D3 receptor | / | 0.447 | |
3w5q | 3KL | Vitamin D3 receptor | / | 0.447 | |
3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.447 | |
4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.447 | |
4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.447 | |
4kfb | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
4rrl | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.447 | |
4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
4uyg | 73B | Bromodomain-containing protein 2 | / | 0.447 | |
4xx0 | COA | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | 6.2.1.4 | 0.447 | |
5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.447 | |
5iub | CLR | Adenosine receptor A2a | / | 0.447 | |
1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
1jtu | LYB | Thymidylate synthase | / | 0.446 | |
1m2p | HNA | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
1rk3 | VDX | Vitamin D3 receptor | / | 0.446 | |
1tdu | DUR | Thymidylate synthase | / | 0.446 | |
1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.446 | |
1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.446 | |
2e07 | SAH | Diphthine synthase | / | 0.446 | |
2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.446 | |
2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.446 | |
2r0p | K2C | Putative FAD-monooxygenase | / | 0.446 | |
2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.446 | |
2wsa | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
2y5s | 78H | Dihydropteroate synthase | / | 0.446 | |
2yx6 | ADP | Uncharacterized protein | / | 0.446 | |
3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.446 | |
3gep | 24H | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.446 | |
3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
3wsb | RWZ | Farnesyltransferase, putative | / | 0.446 | |
4bbh | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.446 | |
4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.446 | |
4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
4gkm | 683 | Anthranilate phosphoribosyltransferase | / | 0.446 | |
4kb8 | 1QO | Casein kinase I isoform delta | 2.7.11.1 | 0.446 | |
4kwi | 1TJ | Reductase homolog | / | 0.446 | |
4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.446 | |
5ify | TRH | Glucose-1-phosphate thymidylyltransferase | / | 0.446 | |
5k2d | ZMA | Adenosine receptor A2a | / | 0.446 | |
1c1b | GCA | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
1dub | CAA | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.445 | |
1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.445 | |
1mk5 | BTN | Streptavidin | / | 0.445 | |
1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.445 | |
1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
1sbr | VIB | Putative HMP/thiamine-binding protein YkoF | / | 0.445 | |
1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.445 | |
1u0h | ONM | Adenylate cyclase type 2 | / | 0.445 | |
1u0h | ONM | Adenylate cyclase type 5 | / | 0.445 | |
2egl | SAH | Diphthine synthase | / | 0.445 | |
2gqf | FAD | Uncharacterized protein HI_0933 | / | 0.445 | |
2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.445 | |
2lfo | GCH | Fatty acid-binding protein, liver | / | 0.445 | |
2rl2 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.445 | |
2xrl | DXT | Tetracycline repressor protein class D | / | 0.445 | |
2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
3dmj | GWE | Pol protein | / | 0.445 | |
3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.445 | |
3kt8 | LTN | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.445 | |
3lu8 | IQX | Serum albumin | / | 0.445 | |
3tfn | 2CJ | Dehydrosqualene synthase | / | 0.445 | |
3vt5 | YI2 | Vitamin D3 receptor | / | 0.445 | |
3w0g | W07 | Vitamin D3 receptor | / | 0.445 | |
3zvu | A8S | Abscisic acid receptor PYR1 | / | 0.445 | |
4at5 | MUJ | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.445 | |
4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.445 | |
4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.445 | |
4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.445 | |
4rrk | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.445 | |
5gcn | COA | HAT A1 | / | 0.445 | |
1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.444 | |
1fw0 | KAI | Glutamate receptor 2 | / | 0.444 | |
1lbb | KAI | Glutamate receptor 2 | / | 0.444 | |
1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
2bdy | UNB | Prothrombin | 3.4.21.5 | 0.444 | |
2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.444 | |
2jf9 | OHT | Estrogen receptor | / | 0.444 | |
2wdq | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.444 | |
2wdq | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.444 | |
2wgj | VGH | Hepatocyte growth factor receptor | 2.7.10.1 | 0.444 | |
2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.444 | |
3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
3fu8 | 3DM | Laccase-1 | 1.10.3.2 | 0.444 | |
3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
3kb0 | A8S | Abscisic acid receptor PYL2 | / | 0.444 | |
3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.444 | |
3pre | 3RE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.444 | |
4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.444 | |
4j26 | EST | Estrogen receptor beta | / | 0.444 | |
4lga | A2O | Abscisic acid receptor PYL2 | / | 0.444 | |
4rgs | V55 | Repressor protein | / | 0.444 | |
5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.444 | |
1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
1cjt | FOK | Adenylate cyclase type 2 | / | 0.443 | |
1cjt | FOK | Adenylate cyclase type 5 | / | 0.443 | |
1cul | FOK | Adenylate cyclase type 2 | / | 0.443 | |
1cul | FOK | Adenylate cyclase type 5 | / | 0.443 | |
1jg0 | DDT | Thymidylate synthase | / | 0.443 | |
1kuv | CA5 | Serotonin N-acetyltransferase | / | 0.443 | |
1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
1s4e | ADP | Galactokinase | / | 0.443 | |
1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
1t4v | 14A | Prothrombin | 3.4.21.5 | 0.443 | |
1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.443 | |
2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.443 | |
2fto | TMP | Thymidylate synthase | / | 0.443 | |
2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.443 | |
2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
2h00 | SAH | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase | / | 0.443 | |
2h6i | CYS_VAL_LEU_SER_GER | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
2ihu | TP9 | N(2)-(2-carboxyethyl)arginine synthase | / | 0.443 | |
2o4r | VD5 | Vitamin D3 receptor | / | 0.443 | |
2pnu | ENM | Androgen receptor | / | 0.443 | |
2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.443 | |
2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.443 | |
3a78 | 3EV | Vitamin D3 receptor | / | 0.443 | |
3d5f | L41 | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.443 | |
3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.443 | |
3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.443 | |
3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.443 | |
3lqf | NAD | Galactitol dehydrogenase | / | 0.443 | |
3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
3pgi | F41 | Endothiapepsin | 3.4.23.22 | 0.443 | |
3tx1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.443 | |
3wo0 | ADP | Alanine--anticapsin ligase | / | 0.443 | |
3zsg | T75 | Mitogen-activated protein kinase 14 | / | 0.443 | |
4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.443 | |
4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.443 | |
4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.443 | |
4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.443 | |
4ixd | 1HV | Integrin alpha-L | / | 0.443 | |
4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
4ruj | VDX | Vitamin D3 receptor A | / | 0.443 | |
4v01 | 0LI | Fibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b | / | 0.443 | |
5a3c | NAD | SIR2 family protein | / | 0.443 | |
5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.443 | |
3uzc | T4E | Adenosine receptor A2a | / | 0.443 | |
1d3d | BZT | Prothrombin | 3.4.21.5 | 0.442 | |
1f5f | DHT | Sex hormone-binding globulin | / | 0.442 | |
1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
1jx0 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.442 | |
1rjk | VDZ | Vitamin D3 receptor | / | 0.442 | |
1x8l | OXR | Retinol dehydratase | / | 0.442 | |
2cle | F6F | Tryptophan synthase alpha chain | / | 0.442 | |
2e95 | B75 | Geranylgeranyl pyrophosphate synthase | / | 0.442 | |
2eka | SAH | Diphthine synthase | / | 0.442 | |
2giu | FBR | Estrogen receptor beta | / | 0.442 | |
2hg1 | N5O | Endoplasmin | / | 0.442 | |
2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.442 | |
2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.442 | |
2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.442 | |
2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.442 | |
2xvv | 9DN | Serum albumin | / | 0.442 | |
3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.442 | |
3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.442 | |
3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.442 | |
3q0g | BCO | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.442 | |
3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.442 | |
4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.442 | |
4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
4egn | TWO | Cytochrome P450 | / | 0.442 | |
4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.442 | |
4ia7 | BIV | Vitamin D3 receptor A | / | 0.442 | |
4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.442 | |
4lsj | LSJ | Glucocorticoid receptor | / | 0.442 | |
4mv3 | ACP | Biotin carboxylase | 6.3.4.14 | 0.442 | |
4uyf | 73B | Bromodomain-containing protein 2 | / | 0.442 | |
5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.442 | |
5iu4 | ZMA | Adenosine receptor A2a | / | 0.442 | |
1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
1flm | FMN | FMN-binding protein | / | 0.441 | |
1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
1kqw | RTL | Cellular retinol-binding protein type II | / | 0.441 | |
1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
1rq1 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.441 | |
1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.441 | |
1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.441 | |
2d0k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
2vnk | FAD | NADPH:ferredoxin reductase | / | 0.441 | |
2zl9 | VDA | Vitamin D3 receptor | / | 0.441 | |
3ezr | EZR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
3fsu | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.441 | |
3gb4 | D3M | DdmC | / | 0.441 | |
3hav | ATP | Aminoglycoside phosphotransferase | / | 0.441 | |
3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.441 | |
3uim | ANP | BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 | 2.7.10.1 | 0.441 | |
3zux | TCH | Transporter | / | 0.441 | |
4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.441 | |
4ffr | ATP | Uncharacterized protein | / | 0.441 | |
4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.441 | |
4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.441 | |
4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.441 | |
4y1b | NAP | AntE | / | 0.441 | |
5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.441 | |
3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.441 | |
1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
1jr4 | CL4 | Catechol O-methyltransferase | 2.1.1.6 | 0.440 | |
1o2g | 696 | Prothrombin | 3.4.21.5 | 0.440 | |
1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.440 | |
1qoq | IGP | Tryptophan synthase alpha chain | / | 0.440 | |
1rt7 | UC4 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
1swt | BTN | Streptavidin | / | 0.440 | |
1thn | ADP | Anti-sigma F factor | / | 0.440 | |
1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.440 | |
2bxm | IMN | Serum albumin | / | 0.440 | |
2dv3 | SAH | Diphthine synthase | / | 0.440 | |
2har | OCC | Vitamin D3 receptor | / | 0.440 | |
2qe4 | JJ3 | Estrogen receptor | / | 0.440 | |
2rki | TT1 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
2rto | IMI | Streptavidin | / | 0.440 | |
2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.440 | |
2zfq | 45U | Prothrombin | 3.4.21.5 | 0.440 | |
2zre | AGS | Protein RecA | / | 0.440 | |
3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
3iis | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.440 | |
3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.440 | |
4ckc | SAH | mRNA-capping enzyme catalytic subunit | 2.1.1.56 | 0.440 | |
4enh | FVX | Cholesterol 24-hydroxylase | / | 0.440 | |
4i7f | NVE | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.440 | |
4py6 | R78 | Bromodomain protein, putative | / | 0.440 | |
5cb5 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.440 |