sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
5mht	SAH	Modification methylase HhaI	2.1.1.37

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
5mht	SAH	Modification methylase HhaI	2.1.1.37	1.000
8mht	SAH	Modification methylase HhaI	2.1.1.37	0.776
7mht	SAH	Modification methylase HhaI	2.1.1.37	0.680
2uyh	SAH	Modification methylase HhaI	2.1.1.37	0.649
2c7q	SAH	Modification methylase HhaI	2.1.1.37	0.592
3mht	SAH	Modification methylase HhaI	2.1.1.37	0.585
1mht	SAH	Modification methylase HhaI	2.1.1.37	0.575
2zcj	SAH	Modification methylase HhaI	2.1.1.37	0.569
2z6u	SAH	Modification methylase HhaI	2.1.1.37	0.476
1skm	SAH	Modification methylase HhaI	2.1.1.37	0.455
9mht	SAH	Modification methylase HhaI	2.1.1.37	0.445