sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
5k2b	ZMA	Adenosine receptor A2a

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
5k2b	ZMA	Adenosine receptor A2a	/	1.000
5uvi	ZMA	Adenosine receptor A2a	/	0.682
5k2d	ZMA	Adenosine receptor A2a	/	0.599
5k2c	ZMA	Adenosine receptor A2a	/	0.598
5k2a	ZMA	Adenosine receptor A2a	/	0.580
5iua	6DX	Adenosine receptor A2a	/	0.565
5jtb	ZMA	Adenosine receptor A2a	/	0.543
4eiy	ZMA	Adenosine receptor A2a	/	0.508
5iu8	6DZ	Adenosine receptor A2a	/	0.502
3eml	ZMA	Adenosine receptor A2a	/	0.500
5iu4	ZMA	Adenosine receptor A2a	/	0.490
5iub	CLR	Adenosine receptor A2a	/	0.462
2ydv	NEC	Adenosine receptor A2a	/	0.457